A redox-dependent thiol-switch and a Ca

Binding Sites / genetics Cell Adhesion Integrins / genetics Ligands Oxidation-Reduction Sulfhydryl Compounds
Adhesion force Ca2+ complexation Cell migration Integrin Integrin conformation Redox-regulation

Journal

Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159

Informations de publication

Date de publication:
07 2022
Historique:
received: 13 04 2022
accepted: 17 05 2022
pubmed: 24 5 2022
medline: 22 6 2022
entrez: 23 5 2022
Statut: ppublish

Résumé

Integrin-mediated cell contacts with the extracellular matrix (ECM) are essential for cellular adhesion, force transmission, and migration. Several effectors, such as divalent cations and redox-active compounds, regulate ligand binding activities of integrins and influence their cellular functions. To study the role of the Ca

Identifiants

DOI: 10.1016/j.freeradbiomed.2022.05.013 PMID: 35605898
pubmed: 35605898
pii: S0891-5849(22)00195-2
doi: 10.1016/j.freeradbiomed.2022.05.013
pii:
doi:

Substances chimiques

Integrins 0
Ligands 0
Sulfhydryl Compounds 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

38-49

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Michele F Caliandro (MF)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Felix Schmalbein (F)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Luca Matteo Todesca (LM)

University of Münster, Institute of Physiology II, Robert-Koch-Str. 27b, 48149, Münster, Germany.

Matthias Mörgelin (M)

em(3), 23170, Anderslöv, Sweden.

Maryam Rezaei (M)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Juliane Meißner (J)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Isabel Siepe (I)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Julius Grosche (J)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany.

Albrecht Schwab (A)

University of Münster, Institute of Physiology II, Robert-Koch-Str. 27b, 48149, Münster, Germany.

Johannes A Eble (JA)

University of Münster, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstr. 15, 48149, Münster, Germany. Electronic address: eblej@uni-muenster.de.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › A redox-dependent thiol-switch and a Ca
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Adhérence cellulaire › A redox-dependent thiol-switch and a Ca
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Intégrines › A redox-dependent thiol-switch and a Ca
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › A redox-dependent thiol-switch and a Ca
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › A redox-dependent thiol-switch and a Ca
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiols › A redox-dependent thiol-switch and a Ca