Antioxidant potential and molecular docking of bioactive compound of Camellia sinensis and Camellia assamica with cytochrome P450.
Antioxidant
Cytochrome P450
FT-IR
Flavonoids
Molecular docking
Journal
Archives of microbiology
ISSN: 1432-072X
Titre abrégé: Arch Microbiol
Pays: Germany
ID NLM: 0410427
Informations de publication
Date de publication:
26 May 2022
26 May 2022
Historique:
received:
19
03
2022
accepted:
27
04
2022
entrez:
26
5
2022
pubmed:
27
5
2022
medline:
31
5
2022
Statut:
epublish
Résumé
Camellia sinensis and Camellia assamica are well known for their medicinal and therapeutic potential. The purpose of this work is to assess the flavonoid content and antioxidant potential of methanol extracts of C. sinensis (MES) and acetone extract of C. assamica (AEA) experimentally and computationally. Qualitative analysis was done to assess the presence of flavonoids. Further, the antioxidant potential of MES and AEA was done by ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) and superoxide free radical-scavenging activity. The profiling of functional groups was analyzed by FT-IR analysis. The bioactive compounds n-heptadecanol-1 of MES and 2',6'-dihydroxyacetophenone, bis(trimethylsilyl) ether of AEA were procured from our previous study to analyze their antioxidant potential computationally (Auto-dock Vina). Both the extracts showed their potential to neutralize free radicals with variable potency. The study of the molecular interactions revealed that both the extracts MES and AEA interacted to the active site with higher binding energy. This work deduced that n-heptadecanol-1 and 2',6'-dihydroxyacetophenone, bis(trimethylsilyl) ether have good potential to inhibit and scavenge the free radicals.
Identifiants
pubmed: 35616739
doi: 10.1007/s00203-022-02949-z
pii: 10.1007/s00203-022-02949-z
doi:
Substances chimiques
Antioxidants
0
Ethers
0
Flavonoids
0
Plant Extracts
0
Cytochrome P-450 Enzyme System
9035-51-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
350Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Almajano MP, Carbo R, Jiménez JAL, Gordon MH (2008) Antioxidant and antimicrobial activities of tea infusions. Food Chem 108(1):55–63
doi: 10.1016/j.foodchem.2007.10.040
Anand J, Rai N, Kumar N, Gautam P (2012) Green tea: a magical herb with miraculous outcomes. Int Res J Pharm 3:139–147
Baravalia Y, Kaneria M, Vaghasiya Y, Parekh J, Chanda S (2009) Antioxidant and antibacterial activity of Diospyros ebenum Roxb. Leaf Extracts Turk J Biol 33(2):159–164
Bhattacharya S (2015) Reactive oxygen species and cellular defense system. Free radicals in human health and disease. Springer, New Delhi, pp 17–29
de Camargo AC, Regitano-d’Arce MAB, Biasoto ACT, Shahidi F (2016) Enzyme-assisted extraction of phenolics from winemaking by-products: antioxidant potential and inhibition of alpha-glucosidase and lipase activities. Food Chem 212:395–402
doi: 10.1016/j.foodchem.2016.05.047
Deba F, Xuan TD, Yasuda M, Tawata S (2008) Chemical composition and antioxidant, antibacterial and antifungal activities of the essential oils from Bidens pilosa Linn. Var. Radiata. Food Control 19(4):346–352
doi: 10.1016/j.foodcont.2007.04.011
Ekayanti M, Ardiana L, Najib SZ, Sauriasari R, Elya B (2017) Pharmacognostic and phytochemical standardization of white tea leaf (Camellia sinensis L. Kuntze) ethanolic extracts. Pharmacog J 9(2):221–226
doi: 10.5530/pj.2017.2.37
Gramza A, Korczak J (2004) Tea extracts influence on catalytical properties of Fe2C in lipids. Pol J Environ Stud 13:143–146
Gramza A, Korczak J (2005) Tea constituents (Camellia sinensis L.) as antioxidants in lipid systems. Trends Food Sci Technol 16(8):351–358
doi: 10.1016/j.tifs.2005.02.004
Hall C (2001) Sources of natural antioxidants: oilseeds, nuts, cereals, legumes, animal products and microbial sources. In: Pokorny J, Yanishlieva N, Gordon M (eds) Antioxidants in food: practical applications. Woodhead Publishing Limited, Cambridge, pp 159–209
doi: 10.1016/9781855736160.3.159
Hausteen BH (2005) The biochemistry and medical significance of the flavonoids. Pharmacol Ther J 96(2–3):67–202
Higdon JV, Frei B (2003) Tea catechins and polyphenols: health effects, metabolism and antioxidant functions. Crit Rev Food Sci Nutr 43(1):89–143
doi: 10.1080/10408690390826464
Hodgson JM, Proudfoot JM, Croft KD, Puddey IB, Mori TA, Beilin LJ (1999) Comparison of the effect of black and green tea in vitro lipoprotein oxidation in human serum. J Sci Food Agr 79:561–566
doi: 10.1002/(SICI)1097-0010(19990315)79:4<561::AID-JSFA218>3.0.CO;2-X
Ignat I, Volf I, Popa VIA (2011) Critical review of methods for characterisation of polyphenolic compounds in fruits and vegetables. Food Chem 126(4):821–1835
doi: 10.1016/j.foodchem.2010.12.026
Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-Okeng JW (2010) Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J Med Plants Res 4(9):753–757
Khalaf NA, Shakya AK, Al-Othman A, El-Agbar Z, Farah H (2008) Antioxidant activity of some common plants. Tur J Biol 32(1):51–55
Khettaf A, Belloula N, Dridi S (2016) Antioxidant activity, phenolic and flavonoid contents of some wild medicinal plants in southeastern Algeria. Afr J Biotechnol 15(13):524–530
doi: 10.5897/AJB2015.14459
Kumar D, Arya V, Kaur R, Bhat ZA, Gupta VK, Kumar V (2012) A review of immunomodulators in the Indian traditional health care system. J Microbiol Immunol Infect 45(3):165–184
doi: 10.1016/j.jmii.2011.09.030
Lefahal M, Zaabat N, Ayad R, Makhloufi EH, Djarri L, Benahmed M, Akkal S (2018) In vitro assessment of total phenolic and flavonoid contents, antioxidant and photoprotective activities of crude methanolic extract of aerial parts of Capnophyllum peregrinum (L.) Lange (Apiaceae) Growing in Algeria. Med 5(2):26–36
Leung LK, Su Y, Chen R, Zhang Z, Huang Y, Chen ZY (2001) Theaflavins in black tea and catechins in green tea are equally effective antioxidants. J Nutr 131:2248–2251
doi: 10.1093/jn/131.9.2248
Li X, Chen S, Li JE, Wang N, Liu X, An Q, Ouyang KH (2019) Chemical composition and antioxidant activities of polysaccharides from Yingshan cloud mist tea. Oxid Med Cell Longev
Li-Weber M (2009) New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituent Wogonin, Baicalein and Bacalin. Cancer Treat Rev 35(1):57–68
doi: 10.1016/j.ctrv.2008.09.005
Lobo V, Patil A, Phatak A, Chandra N (2010) Free radicals, antioxidants and functional foods: impact on human health. Pharmacog Rev 4(8):118–126
doi: 10.4103/0973-7847.70902
Lu Y, Foo LY (2000) Antioxidant and radical scavenging activities of polyphenols from apple pomace. Food Chem 68(1):81–85
doi: 10.1016/S0308-8146(99)00167-3
Pereira VP, Knor FJ, Vellosa JCR, Beltrame FL (2014) Determination of phenolic compounds and antioxidant activity of green, black and white teas of Camellia sinensis (L.) Kuntze, Theaceae. Revista Brasileira De Plantas Medicinais. 16(3):490–498
doi: 10.1590/1983-084X/13_061
Pradhan S, Dubey RC (2020) Evaluation of phytochemical, antimicrobial and time-killing assay of Camellia species. Vegetos 33(4):759–765
doi: 10.1007/s42535-020-00153-2
Pradhan S, Dubey RC (2021) GC–MS analysis and molecular docking of bioactive compounds of Camellia sinensis and Camellia assamica. Arch Microbiol 203(5):2501–2510
doi: 10.1007/s00203-021-02209-6
Rahman K (2007) Studies on free radicals, antioxidants, and co-factors. Clin Interv Aging 2(2):219
pubmed: 18044138
pmcid: 2684512
Rezvanfar MA, Rezvanfar MA, Shahverdi AR, Ahmadi A, Baeeri M, Mohammadirad A, Abdollahi M (2013) Protection of cisplatin-induced spermatotoxicity, DNA damage and chromatin abnormality by selenium nano-particles. Toxicol Appl Pharmacol 266(3):356–365
doi: 10.1016/j.taap.2012.11.025
Sharangi AB (2009) Medicinal and therapeutic potentialities of tea (Camellia sinensis L.)—a review. Food Res Int 42(5–6):529–535
doi: 10.1016/j.foodres.2009.01.007
Sisein EA (2014) Biochemistry of free radicals and antioxidants. Scholars Acad J Biosci 2(2):110–118
Song HJ, Kim YD, Jeong MJ, Ahn MS, Kim SW, Liu JR, Choi MS (2015) Rapid selection of theanine-rich green tea (Camellia sinensis L.) trees and metabolites profiling by Fourier transform near-infrared (FT-IR) spectroscopy. Plant Biotechnol Rep 9(2):55–65
doi: 10.1007/s11816-015-0344-9
Thielecke F, Boschmann M (2009) The potential role of green tea catechins in the prevention of the metabolic syndrome—a review. Phytochem 70(1):11–24
doi: 10.1016/j.phytochem.2008.11.011
Tripathi YC, Jhumka Z, Anjum N (2015) Evaluation of total polyphenol and antioxidant activity of leaves of Bambusa nutans and Bambusa vulgaris. J Pharm Res 9(4):271–277
Vishnoi H, Bodla RB, Kant R, Bodla RB (2018) Green tea (Camellia sinensis) and its antioxidant property: a review. Int J Pharm Sci Res 9(5):1723–1736
Wang XS, Tang CH, Li BS, Yang XQ, Li L, Ma CY (2008) Effects of high-pressure treatment on some physicochemical and functional properties of soy protein isolates. Food Hydrocoll 22(4):560–567
doi: 10.1016/j.foodhyd.2007.01.027
Wickens AP (2001) Aging and the free radical theory. Respir Physiol 128(3):379–391
doi: 10.1016/S0034-5687(01)00313-9