Analysis of Patients with Alcohol Dependence Treated in Silesian Intensive Care Units.
ICU
alcohol dependency
mortality
neurological injury
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
12 05 2022
12 05 2022
Historique:
received:
11
04
2022
revised:
06
05
2022
accepted:
11
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
1
6
2022
Statut:
epublish
Résumé
Analysis of patients with alcohol dependence (AD) treated in intensive care units has never been performed in Poland. Data from 25,416 adult patients identified in a Silesian Registry of Intensive Care Units were analysed. Patients with AD were identified, and their data were compared with the remaining population. Preadmission and admission variables that independently influenced ICU death in these patients were identified. Among 25,416 analysed patients, 2285 subjects (9.0%) were indicated to have AD among their comorbidities. Patients with AD were significantly younger (mean age: 53.3 ± 11.9 vs. 62.2 ± 15.5 years, p < 0.001) but had a higher mean APACHE II score at admission and were more frequently admitted to the ICU due to trauma, poisonings, acute pancreatitis, and severe metabolic abnormalities. ICU death and unfavourable outcomes were more frequent in these patients (47.8% vs. 43.0%, p < 0.001 and 54.1% vs. 47.0%, p < 0.001, respectively). Multiorgan failure as the primary cause of ICU admission was among the most prominent independent risk factors for ICU death in these patients (OR: 3.30, p < 0.001). Despite the younger age, ICU treatment of patients with AD was associated with higher mortality and a higher percentage of unfavourable outcomes.
Identifiants
pubmed: 35627451
pii: ijerph19105914
doi: 10.3390/ijerph19105914
pmc: PMC9140825
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
J Surg Res. 2000 Jun 1;91(1):89-94
pubmed: 10816356
Crit Care. 2019 Dec 5;23(1):393
pubmed: 31805988
Alcohol Clin Exp Res. 2019 Nov;43(11):2431-2437
pubmed: 31596516
J Artif Organs. 2018 Sep;21(3):293-299
pubmed: 29464442
Alcohol Res Health. 2003;27(3):220-31
pubmed: 15535450
Intensive Care Med. 2017 Sep;43(9):1430-1432
pubmed: 28484784
Int J Environ Res Public Health. 2021 Oct 14;18(20):
pubmed: 34682555
PLoS One. 2021 Oct 28;16(10):e0259061
pubmed: 34710137
World J Crit Care Med. 2016 Feb 04;5(1):27-35
pubmed: 26855891
Intern Med J. 2021 Sep;51(9):1433-1440
pubmed: 33470000
Sci Rep. 2020 Oct 21;10(1):17891
pubmed: 33087781
Alcohol Res. 2018;39(2):171-180
pubmed: 31198656
BMJ Open. 2016 Apr 05;6(4):e009944
pubmed: 27048633
Alcohol Clin Exp Res. 2007 Jul;31(7):1224-30
pubmed: 17511746
Addiction. 2019 Sep;114(9):1670-1678
pubmed: 31309639
Acta Anaesthesiol Scand. 2005 Oct;49(9):1236-40
pubmed: 16146458
Crit Care Med. 2007 Feb;35(2):345-50
pubmed: 17205003
J Crit Care. 2020 Jun;57:91-96
pubmed: 32062291
Nutrients. 2021 Sep 11;13(9):
pubmed: 34579046
Anaesthesiol Intensive Ther. 2020;52(1):28-33
pubmed: 32191827
Pancreatology. 2017 Mar - Apr;17(2):155-165
pubmed: 28159463
Subst Abuse. 2019 Sep 12;13:1178221819869327
pubmed: 31548794
Anaesthesia. 2012 Oct;67(10):1132-7
pubmed: 22804562
J Emerg Med. 2021 Dec;61(6):658-665
pubmed: 34711442
Crit Care. 2015 Apr 22;19:185
pubmed: 25899245
Anaesth Intensive Care. 2018 Jan;46(1):58-66
pubmed: 29361257
J Head Trauma Rehabil. 2017 May/Jun;32(3):E65-E74
pubmed: 27455436
Intensive Care Med. 2017 Nov;43(11):1745-1746
pubmed: 28733717
Anaesthesiol Intensive Ther. 2017;49(1):73-75
pubmed: 28362034
Eur J Anaesthesiol. 2018 Dec;35(12):949-954
pubmed: 30234666
Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):164S-170S
pubmed: 11391067
JAMA. 1996 Jan 3;275(1):50-4
pubmed: 8531287
Eur Addict Res. 2015;21(1):6-18
pubmed: 25342593