Feasibility of Magnetic Resonance-Guided High-Intensity-Focused Ultrasound (MRgHIFU) Ablation of Stump Neuromas for the Relief of Chronic Postamputation Neuropathic Pain.
nerve block
neuropathic pain
phantom pain
residual limb pain
thermal ablation
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
revised:
12
04
2022
received:
04
12
2021
accepted:
08
05
2022
pubmed:
29
5
2022
medline:
22
11
2022
entrez:
28
5
2022
Statut:
ppublish
Résumé
Up to 70% of limb amputees develop chronic postamputation neuropathic pain (CPANP) which includes phantom pain and residual limb neuropathic pain due to neuroma formation. CPANP often requires invasive procedures aimed at neuroma ablation. Five amputees received 6 noninvasive magnetic resonance-guided high-intensity-focused ultrasound MRgHIFU treatments ExAblate®, Insightec, Tirat-Carmel, Israel). Although ablative temperature (>65°C) at the neuroma was reached in only 1 patient, pain intensity dropped from 5.7 at baseline to 4.3 and back to 5.6 at 3 and 6 month follow-up. Post-treatment bone necrosis was demonstrated in 1 patient. Although no firm conclusion about the effectiveness of MRgHIFU for CPANP could be drawn, further studies are warranted.
Identifiants
pubmed: 35633227
doi: 10.1002/jum.16026
pmc: PMC9796504
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
3119-3124Subventions
Organisme : Focused Ultrasound Foundation
Informations de copyright
© 2022 The Authors. Journal of Ultrasound in Medicine published by Wiley Periodicals LLC on behalf of American Institute of Ultrasound in Medicine.
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