Gene reporters for magnetic resonance imaging.

Genes, Reporter / genetics Image Enhancement / methods Magnetic Resonance Imaging / methods
MRI diffusion exchange gene reporters relaxation

Journal

Trends in genetics : TIG
ISSN: 0168-9525
Titre abrégé: Trends Genet
Pays: England
ID NLM: 8507085

Informations de publication

Date de publication:
10 2022
Historique:
received: 01 04 2022
revised: 04 05 2022
accepted: 05 05 2022
pubmed: 1 6 2022
medline: 16 9 2022
entrez: 31 5 2022
Statut: ppublish

Résumé

MRI-based gene reporters allow imaging of gene expression at depth (tens of centimetres) and at relatively high resolution (~10-100 μm) and have the potential to be translated to the clinic. The reporters exploit either endogenous contrast mechanisms or they modulate the response to an introduced exogenous contrast agent.

Identifiants

DOI: 10.1016/j.tig.2022.05.006 PMID: 35641343
pubmed: 35641343
pii: S0168-9525(22)00114-7
doi: 10.1016/j.tig.2022.05.006
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

996-998

Informations de copyright

Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

Kevin M Brindle (KM)

Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, UK. Electronic address: kmb1001@cam.ac.uk.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes rapporteurs › Gene reporters for magnetic resonance imaging.
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Traitement d'image par ordinateur › Amélioration d'image › Gene reporters for magnetic resonance imaging.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Gene reporters for magnetic resonance imaging.