Primary Graft Dysfunction: The Role of Aging in Lung Ischemia-Reperfusion Injury.

aging ischemia reperfusion injury lung transplantation primary graft dysfunction senolytics

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 07 03 2022
accepted: 21 04 2022
entrez: 10 6 2022
pubmed: 11 6 2022
medline: 14 6 2022
Statut: epublish

Résumé

Transplant centers around the world have been using extended criteria donors to remedy the ongoing demand for lung transplantation. With a rapidly aging population, older donors are increasingly considered. Donor age, at the same time has been linked to higher rates of lung ischemia reperfusion injury (IRI). This process of acute, sterile inflammation occurring upon reperfusion is a key driver of primary graft dysfunction (PGD) leading to inferior short- and long-term survival. Understanding and improving the condition of older lungs is thus critical to optimize outcomes. Notably,

Identifiants

pubmed: 35686120
doi: 10.3389/fimmu.2022.891564
pmc: PMC9170999
doi:

Types de publication

Journal Article Review Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

891564

Subventions

Organisme : NIA NIH HHS
ID : R01 AG064165
Pays : United States

Informations de copyright

Copyright © 2022 Roesel, Sharma, Schroeter, Matsunaga, Xiao, Zhou and Tullius.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

J Heart Lung Transplant. 2001 Dec;20(12):1291-6
pubmed: 11744412
Am J Physiol Lung Cell Mol Physiol. 2009 Mar;296(3):L462-9
pubmed: 19074557
J Mol Cell Cardiol. 2009 Jun;46(6):775-80
pubmed: 19303419
Chest. 2000 Nov;118(5):1255-62
pubmed: 11083672
J Surg Res. 2012 Jan;172(1):153-8
pubmed: 20888591
Nephrol Dial Transplant. 2004 Jun;19 Suppl 3:iii11-5
pubmed: 15192129
Int Rev Immunol. 2011 Feb;30(1):16-34
pubmed: 21235323
J Surg Res. 2014 Mar;187(1):289-96
pubmed: 24238972
Annu Rev Pathol. 2010;5:99-118
pubmed: 20078217
Am J Respir Crit Care Med. 2015 Feb 15;191(4):455-63
pubmed: 25485813
Am J Transplant. 2021 Feb;21 Suppl 2:441-520
pubmed: 33595190
J Appl Physiol (1985). 1995 Jun;78(6):2245-52
pubmed: 7665425
J Heart Lung Transplant. 2019 Oct;38(10):1042-1055
pubmed: 31548030
Circulation. 2015 Jul 14;132(2):122-31
pubmed: 25957225
N Engl J Med. 2011 Apr 14;364(15):1431-40
pubmed: 21488765
JAMA Surg. 2015 Jun;150(6):547-53
pubmed: 25874575
EBioMedicine. 2017 Jul;21:21-28
pubmed: 28416161
Transplant Direct. 2021 Jan 07;7(2):e652
pubmed: 33437867
Am J Respir Cell Mol Biol. 2000 Jun;22(6):657-64
pubmed: 10837361
J Thorac Cardiovasc Surg. 2005 Apr;129(4):919-25
pubmed: 15821664
Transplant Rev (Orlando). 2020 Jul;34(3):100549
pubmed: 32498978
Cell. 2021 Apr 15;184(8):1990-2019
pubmed: 33811810
Transplantation. 2013 Feb 15;95(3):513-8
pubmed: 23202531
Adv Exp Med Biol. 2017;967:195-225
pubmed: 29047088
Surgery. 2013 Feb;153(2):249-61
pubmed: 23059113
Transplant Proc. 1999 Feb-Mar;31(1-2):1298-9
pubmed: 10083579
J Heart Lung Transplant. 2000 Dec;19(12):1199-204
pubmed: 11124490
J Thorac Cardiovasc Surg. 2007 Feb;133(2):554-9
pubmed: 17258599
N Engl J Med. 1999 Apr 8;340(14):1081-91
pubmed: 10194239
Antioxid Redox Signal. 2014 May 1;20(13):2043-58
pubmed: 24070031
Lancet Respir Med. 2018 May;6(5):357-367
pubmed: 29650408
Front Immunol. 2021 Sep 09;12:681504
pubmed: 34566955
Front Cardiovasc Med. 2018 Feb 13;5:8
pubmed: 29487855
Am J Respir Crit Care Med. 2005 Jun 1;171(11):1312-6
pubmed: 15764726
J Heart Lung Transplant. 2013 Oct;32(10):965-78
pubmed: 24054805
J Heart Lung Transplant. 2008 Dec;27(12):1319-25
pubmed: 19059112
Transpl Int. 2010 Jun;23(6):628-35
pubmed: 20059752
Circ Res. 2020 Jan 17;126(2):280-293
pubmed: 31944918
Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1723-41
pubmed: 21856909
Circ Res. 2010 Mar 5;106(4):633-46
pubmed: 20203313
J Thorac Dis. 2014 Aug;6(8):1032-8
pubmed: 25132970
Chest. 2005 Jan;127(1):161-5
pubmed: 15653978
Transplantation. 2021 Dec 1;105(12):2515-2516
pubmed: 34818306
Redox Biol. 2015 Dec;6:524-551
pubmed: 26484802
Cardiovasc Res. 2005 May 1;66(2):233-44
pubmed: 15820192
Transplant Proc. 2006 Oct;38(8):2691-3
pubmed: 17098041
Am J Transplant. 2019 Apr;19(4):1011-1023
pubmed: 30378766
Nat Commun. 2020 Aug 27;11(1):4289
pubmed: 32855397
EBioMedicine. 2019 Feb;40:554-563
pubmed: 30616998
J Heart Lung Transplant. 2017 Oct;36(10):1104-1113
pubmed: 28802530
Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1283-99
pubmed: 20833966
Am J Transplant. 2010 Apr;10(4 Pt 2):973-86
pubmed: 20420647
Ann Thorac Surg. 2017 Nov;104(5):1702-1709
pubmed: 28964417
Eur J Cardiothorac Surg. 2017 Jul 1;52(1):171-177
pubmed: 28874022
J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):219-223
pubmed: 23592133
Transplantation. 2005 May 27;79(10):1445-52
pubmed: 15912118
Semin Cardiothorac Vasc Anesth. 2020 Mar;24(1):34-44
pubmed: 32036756
Ann Surg. 2010 Oct;252(4):662-74
pubmed: 20881773
Curr Opin Organ Transplant. 2020 Jun;25(3):268-273
pubmed: 32332197
Nat Med. 2018 Aug;24(8):1246-1256
pubmed: 29988130
J Clin Med. 2020 Mar 20;9(3):
pubmed: 32244972
J Heart Lung Transplant. 2005 Oct;24(10):1468-82
pubmed: 16210118
Immune Netw. 2018 Aug 13;18(4):e27
pubmed: 30181915
J Heart Lung Transplant. 2017 Oct;36(10):1114-1120
pubmed: 28818404
Physiol Rev. 2014 Jul;94(3):909-50
pubmed: 24987008
Cardiovasc Res. 2001 Aug 1;51(2):241-50
pubmed: 11470463
Biochim Biophys Acta. 2009 Nov;1787(11):1402-15
pubmed: 19168026
Cell Death Dis. 2013 Sep 05;4:e787
pubmed: 24008731
Ann Thorac Surg. 2000 Jun;69(6):1681-5
pubmed: 10892906
Clin Transplant. 2017 Jul;31(7):
pubmed: 28470765
Ann Thorac Surg. 1999 Dec;68(6):2015-9; discussion 2019-20
pubmed: 10616969
Nat Commun. 2012 Jan 31;3:649
pubmed: 22337127
Am J Physiol. 1993 Dec;265(6 Pt 2):H2017-26
pubmed: 8285240
Eur J Anaesthesiol. 2009 Jul;26(7):537-47
pubmed: 19412112
Am J Transplant. 2016 Jun;16(6):1707-14
pubmed: 26813036
Am J Respir Crit Care Med. 2013 Mar 1;187(5):527-34
pubmed: 23306540
J Exp Med. 2000 Oct 2;192(7):1001-14
pubmed: 11015441
Chest. 2002 Jun;121(6):1876-82
pubmed: 12065352
J Heart Lung Transplant. 2017 Oct;36(10):1097-1103
pubmed: 28942784
Am J Transplant. 2021 Dec;21(12):3831-3839
pubmed: 34355495
Aging Cell. 2018 Aug;17(4):e12761
pubmed: 29774638
Semin Respir Crit Care Med. 2010 Apr;31(2):161-71
pubmed: 20354929
Ann Cardiothorac Surg. 2020 Jan;9(1):49-50
pubmed: 32175239
Surg Today. 2006;36(3):205-14
pubmed: 16493527
J Thorac Cardiovasc Surg. 2006 Jan;131(1):73-80
pubmed: 16399297
Cardiovasc Res. 2009 Jul 15;83(2):247-61
pubmed: 19176601
Front Physiol. 2020 Dec 18;11:581420
pubmed: 33391010
Acta Biomater. 2021 Nov;135:520-533
pubmed: 34454081
Ann Thorac Surg. 2021 Feb;111(2):421-426
pubmed: 32663473
Curr Opin Organ Transplant. 2016 Jun;21(3):246-52
pubmed: 26945320
Circ Res. 2014 Jan 31;114(3):524-37
pubmed: 24481843
J Thorac Cardiovasc Surg. 2011 Jan;141(1):215-22
pubmed: 21093882
Can J Anaesth. 2006 Aug;53(8):831-7
pubmed: 16873351
Am J Transplant. 2019 Feb;19 Suppl 2:404-484
pubmed: 30811892
Clin Transplant. 2018 Apr;32(4):e13208
pubmed: 29374425
Gen Thorac Cardiovasc Surg. 2021 Apr;69(4):625-630
pubmed: 33683575
Transplantation. 2002 Jun 15;73(11):1703-6
pubmed: 12084990
Transplantation. 1993 Apr;55(4):807-13
pubmed: 8475556
Clin Transplant. 2009 Nov-Dec;23(6):819-30
pubmed: 19239481
FASEB J. 2019 Feb;33(2):3063-3073
pubmed: 30383439
Cells. 2021 May 28;10(6):
pubmed: 34071255
Int J Mol Sci. 2021 Nov 04;22(21):
pubmed: 34769397
Clin Chest Med. 2017 Dec;38(4):641-654
pubmed: 29128015
Kidney Int. 2007 Apr;71(7):629-36
pubmed: 17264877
Anesthesiology. 2001 Jun;94(6):1133-8
pubmed: 11465607
Ann Thorac Surg. 1999 May;67(5):1428-33; discussion 1434
pubmed: 10355425
Chest. 2003 Oct;124(4):1232-41
pubmed: 14555551
Front Chem. 2020 Aug 21;8:732
pubmed: 32974285
Semin Thorac Cardiovasc Surg. 2008 Summer;20(2):143-51
pubmed: 18707649
Int J Cardiol. 2004 Nov;97(2):263-76
pubmed: 15458694
J Thorac Cardiovasc Surg. 2003 Jul;126(1):200-7
pubmed: 12878956
Am J Transplant. 2021 Feb;21 Suppl 2:521-558
pubmed: 33595189
J Am Soc Nephrol. 2000 Jul;11(7):1317-1324
pubmed: 10864589
Ann Transl Med. 2020 Mar;8(6):412
pubmed: 32355856
Transpl Immunol. 2022 Apr;71:101556
pubmed: 35202801
Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):47-53
pubmed: 25260894
Transpl Int. 2021 Jan;34(1):194-203
pubmed: 33145853
J Immunol. 2015 Nov 15;195(10):4802-9
pubmed: 26475925
Ann N Y Acad Sci. 2005 Jun;1047:248-58
pubmed: 16093501
J Heart Lung Transplant. 2013 Aug;32(8):760-8
pubmed: 23664760
PLoS One. 2014 Mar 21;9(3):e92773
pubmed: 24658073
Lancet. 2002 Aug 24;360(9333):619-20
pubmed: 12241936
Nat Rev Cardiol. 2011 May;8(5):292-300
pubmed: 21448140
Curr Opin Organ Transplant. 2015 Oct;20(5):506-14
pubmed: 26262465
Am J Transplant. 2019 May;19(5):1464-1477
pubmed: 30582269
Transplantation. 2014 Oct 27;98(8):903-8
pubmed: 24825527
Transplant Proc. 2012 Oct;44(8):2462-8
pubmed: 23026621
J Heart Lung Transplant. 1999 May;18(5):425-31
pubmed: 10363686
Am J Physiol Heart Circ Physiol. 2014 Jun 15;306(12):H1602-9
pubmed: 24748594
JCI Insight. 2020 Sep 3;5(17):
pubmed: 32750037
Ann Cardiothorac Surg. 2020 Jan;9(1):1-9
pubmed: 32175234
Proc Am Thorac Soc. 2009 Jan 15;6(1):28-38
pubmed: 19131528
Am J Physiol Heart Circ Physiol. 2015 Mar 1;308(5):H500-9
pubmed: 25527775
J Heart Lung Transplant. 2005 Oct;24(10):1454-9
pubmed: 16210116
Transpl Int. 2015 Feb;28(2):170-9
pubmed: 25266074
FASEB J. 2021 Jan;35(1):e21229
pubmed: 33368613
Int Rev Cell Mol Biol. 2012;298:229-317
pubmed: 22878108
J Heart Lung Transplant. 2007 Oct;26(10):1004-11
pubmed: 17919620

Auteurs

Maximilian J Roesel (MJ)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Institute of Medical Immunology, Charité Universitaetsmedizin Berlin, Berlin, Germany.

Nirmal S Sharma (NS)

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Department of Medicine, Harvard Medical School, Boston, MA, United States.

Andreas Schroeter (A)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Regenerative Medicine and Experimental Surgery, Department of General, Visceral and Transplant Surgery, Hannover Medical School, Hannover, Germany.

Tomohisa Matsunaga (T)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan.

Yao Xiao (Y)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

Hao Zhou (H)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

Stefan G Tullius (SG)

Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

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