7-epi-cylindrospermopsin and microcystin producers among diverse Anabaena/Dolichospermum/Aphanizomenon CyanoHABs in Oregon, USA.
7-epi-cylindrospermopsin
CyanoHAB
Microcystin, homotyrosine
NRPS, specificity prediction
mcy genes
Journal
Harmful algae
ISSN: 1878-1470
Titre abrégé: Harmful Algae
Pays: Netherlands
ID NLM: 101128968
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
received:
11
01
2022
revised:
18
03
2022
accepted:
27
04
2022
entrez:
16
6
2022
pubmed:
17
6
2022
medline:
22
6
2022
Statut:
ppublish
Résumé
Several genomes of Nostocales ADA clade members from the US Pacific Northwest were recently sequenced. Biosynthetic genes for microcystin, cylindrospermopsin or anatoxin-a were present in 7 of the 15 Dolichospermum/Anabaena strains and none of the 5 Aphanizomenon flos-aquae (AFA) strains. Toxin analyses (ELISA and LC-MS/MS) were conducted to quantitate and identify microcystin (MC) and cylindrospermopsin (CYN) congeners/analogs in samples dominated by Dolichospermum spp. of known genome sequence. MC-LR was the main congener produced by Dolichospermum spp. from Junipers Reservoir, Lake Billy Chinook and Odell Lake, while a congener provisionally identified as [Dha
Identifiants
pubmed: 35710201
pii: S1568-9883(22)00069-5
doi: 10.1016/j.hal.2022.102241
pii:
doi:
Substances chimiques
Alkaloids
0
Bacterial Toxins
0
Cyanobacteria Toxins
0
Microcystins
0
cylindrospermopsin
2JIZ556BA3
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102241Informations de copyright
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