Characterization of DAG Binding to TRPC Channels by Target-Dependent

TRPC channels diacylglycerols lipid photopharmacology photoisomerization

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
07 06 2022
Historique:
received: 06 05 2022
revised: 03 06 2022
accepted: 05 06 2022
entrez: 24 6 2022
pubmed: 25 6 2022
medline: 28 6 2022
Statut: epublish

Résumé

Azobenzene-based photochromic lipids are valuable probes for the analysis of ion channel-lipid interactions. Rapid photoisomerization of these molecules enables the analysis of lipid gating kinetics and provides information on lipid sensing. Thermal relaxation of the metastable

Identifiants

pubmed: 35740924
pii: biom12060799
doi: 10.3390/biom12060799
pmc: PMC9221121
pii:
doi:

Substances chimiques

Ion Channels 0
Lipid Bilayers 0
Unilamellar Liposomes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Austrian Science Fund FWF
ID : W 1226
Pays : Austria

Références

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Auteurs

Hazel Erkan-Candag (H)

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging-Division of Biophysics, Medical University Graz, 8010 Graz, Austria.

Denis Krivic (D)

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging-Division of Biophysics, Medical University Graz, 8010 Graz, Austria.
Max Planck Institute of Colloids and Interfaces, 14476 Potsdam, Germany.

Mathias A F Gsell (MAF)

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging-Division of Biophysics, Medical University Graz, 8010 Graz, Austria.

Mina Aleksanyan (M)

Max Planck Institute of Colloids and Interfaces, 14476 Potsdam, Germany.
Institute for Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.

Thomas Stockner (T)

Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.

Rumiana Dimova (R)

Max Planck Institute of Colloids and Interfaces, 14476 Potsdam, Germany.

Oleksandra Tiapko (O)

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging-Division of Biophysics, Medical University Graz, 8010 Graz, Austria.

Klaus Groschner (K)

Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging-Division of Biophysics, Medical University Graz, 8010 Graz, Austria.

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Classifications MeSH