Can deep learning improve image quality of low-dose CT: a prospective study in interstitial lung disease.
Deep learning
Intelligence
Lung diseases, Interstitial
Radiation dosage
Journal
European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
09
02
2022
accepted:
10
05
2022
revised:
11
04
2022
pubmed:
25
6
2022
medline:
1
12
2022
entrez:
24
6
2022
Statut:
ppublish
Résumé
To investigate whether deep learning reconstruction (DLR) could keep image quality and reduce radiation dose in interstitial lung disease (ILD) patients compared with HRCT reconstructed with hybrid iterative reconstruction (hybrid-IR). Seventy ILD patients were prospectively enrolled and underwent HRCT (120 kVp, automatic tube current) and LDCT (120 kVp, 30 mAs) scans. HRCT images were reconstructed with hybrid-IR (Adaptive Iterative Dose Reduction 3-Dimensional [AIDR3D], standard-setting); LDCT images were reconstructed with DLR (Advanced Intelligence Clear-IQ Engine [AiCE], lung/bone, mild/standard/strong setting). Image noise, streak artifact, overall image quality, and visualization of normal and abnormal features of ILD were evaluated. The mean radiation dose of LDCT was 38% of HRCT. Objective image noise of reconstructed LDCT images was 33.6 to 111.3% of HRCT, and signal-to-noise ratio (SNR) was 0.9 to 3.1 times of the latter (p < 0.001). LDCT-AiCE was not significantly different from or even better than HRCT in overall image quality and visualization of normal lung structures. LDCT-AiCE (lung, mild/standard/strong) showed progressively better recognition of ground glass opacity than HRCT-AIDR3D (p < 0.05, p < 0.01, p < 0.001), and LDCT-AiCE (lung, mild/standard/strong; bone, mild) was superior to HRCT-AIDR3D in visualization of architectural distortion (p < 0.01, p < 0.01, p < 0.01; p < 0.05). LDCT-AiCE (bone, strong) was better than HRCT-AIDR3D in the assessment of bronchiectasis and/or bronchiolectasis (p < 0.05). LDCT-AiCE (bone, mild/standard/strong) was significantly better at the visualization of honeycombing than HRCT-AIDR3D (p < 0.05, p < 0.05, p < 0.01). Deep learning reconstruction could effectively reduce radiation dose and keep image quality in ILD patients compared to HRCT with hybrid-IR. • Deep learning reconstruction was a novel image reconstruction algorithm based on deep convolutional neural networks. It was applied in chest CT studies and received auspicious results. • HRCT plays an essential role in the whole process of diagnosis, treatment efficacy evaluation, and follow-ups for interstitial lung disease patients. However, cumulative radiation exposure could increase the risks of cancer. • Deep learning reconstruction method could effectively reduce the radiation dose and keep the image quality compared with HRCT reconstructed with hybrid iterative reconstruction in patients with interstitial lung disease.
Identifiants
pubmed: 35748899
doi: 10.1007/s00330-022-08870-9
pii: 10.1007/s00330-022-08870-9
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8140-8151Informations de copyright
© 2022. The Author(s), under exclusive licence to European Society of Radiology.
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