Pleiotropic effects of trans-regulatory mutations on fitness and gene expression.
Journal
Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
entrez:
30
6
2022
pubmed:
1
7
2022
medline:
6
7
2022
Statut:
ppublish
Résumé
Variation in gene expression arises from cis- and trans-regulatory mutations, which contribute differentially to expression divergence. We compare the impacts on gene expression and fitness resulting from cis- and trans-regulatory mutations in
Identifiants
pubmed: 35771906
doi: 10.1126/science.abj7185
pmc: PMC9569154
mid: NIHMS1840464
doi:
Substances chimiques
Saccharomyces cerevisiae Proteins
0
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)
EC 1.2.1.12
TDH3 protein, S cerevisiae
EC 1.2.1.12
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105-109Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM089736
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM108826
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM118073
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007544
Pays : United States
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