Isonicotinic acid hydrazide (INH) versus extra-amniotic saline infusion (EASI) for cervical ripening at term: a randomised controlled trial.


Journal

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
ISSN: 1364-6893
Titre abrégé: J Obstet Gynaecol
Pays: England
ID NLM: 8309140

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 6 7 2022
medline: 6 1 2023
entrez: 5 7 2022
Statut: ppublish

Résumé

The purpose of this trial was to compare extra-amniotic saline infusion (EASI) and intravaginal isoniazid (INH) for cervical ripening. This randomised clinical trial included 150 pregnant women who were undergoing induction of labour and who required pre-induction cervical ripening. Patients were randomly assigned to receive EASI or intravaginal INH. Bishop's score at the beginning of the study and before oxytocin infusion was not significantly different between INH and EASI groups. However, the time from first intervention to the beginning of the induction and also to the beginning of the active phase were significantly shorter in EASI group (

Identifiants

pubmed: 35786390
doi: 10.1080/01443615.2022.2084370
doi:

Substances chimiques

Oxytocics 0
Isoniazid V83O1VOZ8L
Misoprostol 0E43V0BB57

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2693-2697

Auteurs

Ladan Haghighi (L)

Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Behnaz Mohabbatian (B)

Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Zahra Najmi (Z)

Department of Obstetrics and Gynecology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Samaneh Rokhgireh (S)

Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Samira Saadatjoo (S)

Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Yousef Moradi (Y)

Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Mojgan Mokhtari (M)

Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

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Classifications MeSH