Non-toxigenic Corynebacterium diphtheriae in hallux ulceration.


Journal

Journal of infection in developing countries
ISSN: 1972-2680
Titre abrégé: J Infect Dev Ctries
Pays: Italy
ID NLM: 101305410

Informations de publication

Date de publication:
30 06 2022
Historique:
received: 28 11 2021
accepted: 22 01 2022
entrez: 7 7 2022
pubmed: 8 7 2022
medline: 12 7 2022
Statut: epublish

Résumé

Toxigenic Corynebacterium diphtheriae causes classical diphtheria. Skin infections by toxigenic or non-toxigenic Corynebacterium diphtheriae are prevalent in the tropics but are rarely reported. We report the identification of a non-toxigenic Corynebacterium diphtheriae (biovar Gravis) isolate in a 52-year-old Cambodian male. The patient presented purulent and non-healing ulcerations on the right hallux. The wound has healed after 7 days of antibiotic therapy with a favourable outcome. This case represents, to our knowledge, the first report of Corynebacterium diphtheriae in Cambodia in the last 10 years, and highlights the lack of diagnosis and notifications of diphtheria. It is important to raise awareness among clinicians and to set up diphtheria surveillance in Cambodia.

Identifiants

pubmed: 35797309
doi: 10.3855/jidc.16153
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1118-1121

Informations de copyright

Copyright (c) 2022 Gauthier Delvallez, Edgar Badell, Sokleaph Cheng, Soda Meng, Vivandet Tong, Judy Norman, Julie Toubiana, Koen Vandelannoote, Anne-Laure Bañuls, Mallorie Hide, Sylvain Brisse.

Déclaration de conflit d'intérêts

No Conflict of Interest is declared

Auteurs

Gauthier Delvallez (G)

Medical Biology Laboratory, Institut Pasteur du Cambodge, Phnom Penh, Cambodia. gdelvallez@pasteur-kh.org.

Edgar Badell (E)

Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.

Sokleaph Cheng (S)

Medical Biology Laboratory, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

Soda Meng (S)

Medical Biology Laboratory, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

Vivandet Tong (V)

Mercy Medical Center Cambodia, Phnom Penh, Cambodia.

Judy Norman (J)

Mercy Medical Center Cambodia, Phnom Penh, Cambodia.

Julie Toubiana (J)

Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.

Koen Vandelannoote (K)

Medical Biology Laboratory, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

Anne-Laure Bañuls (AL)

LMI Drug Resistance in South East Asia, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

Mallorie Hide (M)

Medical Biology Laboratory, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

Sylvain Brisse (S)

Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.

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