A self-adjuvanting anti-tumor nanoliposomal vaccine based on fluorine-substituted MUC1 glycopeptide.

Adjuvants, Immunologic / pharmacology Cancer Vaccines / therapeutic use Fluorine Glycopeptides Mucin-1

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
02 Aug 2022
Historique:
pubmed: 13 7 2022
medline: 4 8 2022
entrez: 12 7 2022
Statut: epublish

Résumé

Herein, a self-adjuvanting fluorinated MUC1-based nanoliposomal antitumor vaccine was constructed for the first time. Both the tumor-associated antigen and the mode of its presentation affect the immune response for antitumor vaccines.

Identifiants

DOI: 10.1039/d2cc02143a PMID: 35820186
pubmed: 35820186
doi: 10.1039/d2cc02143a
doi:

Substances chimiques

Adjuvants, Immunologic 0
Cancer Vaccines 0
Glycopeptides 0
Mucin-1 0
Fluorine 284SYP0193

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8642-8645

Auteurs

Peijie Dong (P)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.

Suying Cheng (S)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.

Yudie Wang (Y)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.

Hang Gao (H)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.

Yongmin Zhang (Y)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.
Sorbonne Université, Institut Parisien de Chimie Moléculaire, UMR CNRS 8232, 4 place Jussieu, 75005, Paris, France.
ORCID: 0000-0001-8493-5812

Tao Zhu (T)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.
CanSino Biologics Inc., Tianjin Enterprise Key Laboratory of Respiratory Bacterial Recombination and Conjugated Vaccine, Tianjin 300457, China.

Peng Yu (P)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.

Xin Meng (X)

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Tianjin 300457, P. R. China. mengxin@tust.edu.cn.
ORCID: 0000-0001-7727-6046

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Adjuvants immunologiques › A self-adjuvanting anti-tumor nanoliposomal...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins anticancéreux › A self-adjuvanting anti-tumor nanoliposomal...
questionsmedicales.fr › Produits chimiques inorganiques › Éléments › Halogènes › Fluor › A self-adjuvanting anti-tumor nanoliposomal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Glycopeptides › A self-adjuvanting anti-tumor nanoliposomal...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Antigènes glycanniques associés aux tumeurs › Mucine-1 › A self-adjuvanting anti-tumor nanoliposomal...