Frequent hypoxemia found in infants with bronchopulmonary dysplasia after weaning home oxygen.
bronchopulmonary dysplasia
neonatal pulmonary medicine
oxygenation and therapy
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
revised:
29
06
2022
received:
17
05
2021
accepted:
12
07
2022
pubmed:
15
7
2022
medline:
19
10
2022
entrez:
14
7
2022
Statut:
ppublish
Résumé
Parental reports and brief clinical examinations are the primary information used to assist clinicians in weaning home supplemental oxygen in infants with bronchopulmonary dysplasia (BPD). Recorded nocturnal oximetry provides an objective assessment of hypoxemia; however, it is unknown if it identifies clinically undetected hypoxemia in the home setting. Our objective was to determine if nocturnal oximetry can identify unreported hypoxemia in infants with BPD who appear ready to wean from supplemental oxygen. We conducted a retrospective chart review of infants born <32 weeks gestation with BPD who were discharged to home receiving supplemental oxygen and completed recorded nocturnal oximetry in room air during an 18-month period. Abnormal oximetry was defined as >5 min with SpO Thirty-five former premature infants completed nocturnal oximetry at 5.8 (3.4-8.3) months corrected age. Nocturnal oximetry was abnormal as defined in 67% of the cohort (n = 21). Five percent of patients were hypoxemic, 52% had frequent desaturation events, and 43% had both. No significant differences existed in neonatal characteristics between patients with normal and abnormal studies. Nocturnal oximetry was abnormal in the majority of infants with BPD who were otherwise clinically ready to wean from oxygen support, suggesting that recorded home oximetry could be a feasible and useful tool to evaluate for otherwise clinically unapparent nocturnal hypoxemia in patients with BPD.
Substances chimiques
Oxyhemoglobins
0
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2638-2645Informations de copyright
© 2022 Wiley Periodicals LLC.
Références
Rhein L, Simoneau T, Davis J, et al. Reference values of nocturnal oxygenation for use in outpatient oxygen weaning protocols in premature infants. Pediatr Pulmonol. 2012;47(5):453-459.
Moyer-Mileur LJ, Nielson DW, Pfeffer KD, Witte MK, Chapman DL. Eliminating sleep-associated hypoxemia improves growth in infants with bronchopulmonary dysplasia. Pediatrics. 1996;98(4):779-783.
Groothuis JR, Rosenberg AA. Home oxygen promotes weight gain in infants with bronchopulmonary dysplasia. Am J Dis Child. 1987;141(9):992-995.
Hayes D Jr., Wilson KC, Krivchenia K, et al. Home oxygen therapy for children. Am J Respir Crit Care Med. 2019;199(3):e5-e23.
Manja V, Saugstad OD, Lakshminrusimha S. Oxygen saturation targets in preterm infants and outcomes at 18−24 months: a systematic review. Pediatrics. 2017;139(1):1-14.
Moon NM, Mohay HA, Gray PH. Developmental patterns from 1 to 4 years of extremely preterm infants who required home oxygen therapy. Early Hum Dev. 2006;83:209-216.
Sriram S, Schreiber MD, Msall ME, et al. Cognitive development and quality of life associated with BPD in 10-year-olds born preterm. Pediatrics. 2018;141(6):e20172719.
Di Fiore JM, MacFarlane PM, Martin RJ. Intermittent hypoxemia in preterm infants. Clin Perinatol. 2019;46(3):553-565.
Di Fiore JM, Shah V, Patwardhan A, et al. Prematurity and postnatal alterations in intermittent hypoxaemia. Arch Dis Child Fetal Neonatal Ed. 2021;106:557-559.
Hunt CE, Corwin MJ, Weese-Mayer DE, et al.Longitudinal assessment of hemoglobin oxygen saturation in preterm and term infants in the first six months of life. J Pediatr. 2011;159(3):377-383.e1.
Lagatta JM, Clark RH, Brousseau DC, Hoffmann R, Spitzer A. Varying patterns of home oxygen use in infants at 23-43 weeks' gestation discharged from United States neonatal intensive care units. J Pediatr. 2013;163(4):976-82.e2.
Lagatta J, Murthy K, Zaniletti I, et al. Home oxygen use and 1-year readmission among infants born preterm with bronchopulmonary dysplasia discharged from children's hospital neonatal intensive care units. J Pediatr. 2020;220:40-48.e5.
Cummings JJ, Polin RA, AAP Committee on Fetus and Newborn. Oxygen targeting in extremely low birth weight infants. Pediatrics. 2016;138(2):e2-e9.
Brouillette RT, Morielli A, Leimanis A, Waters KA, Luciano R, Ducharme FM. Nocturnal pulse oximetry as an abbreviated testing modality for pediatric obstructive sleep apnea. Pediatrics. 2000;105(2):405-412.
Ehsan Z, He S, Huang G, Hossain M, Simakajornboon N. Can overnight portable pulse oximetry be used to stratify obstructive sleep apnea risk in infants? A correlation analysis. Pediatr Pulmonol. 2020;55(8):2082-2088.
Procaskey A, White H, Simoneau T, et al. The optimization of home oxygen weaning in premature infants trial: design, rationale, methods, and lessons learned. Contemp Clin Trials. 2018;75:72-77.
Flint A, Davies M. The use of overnight oximetry in neonates: a literature review. J Paediatr Child Health. 2018;54:720-727.
Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2001;163(7):1723-1729.
Ito E, Inoue Y. International Classification of Sleep Disorders. 3rd ed. American Academy of Sleep Medicine; 2014.
Marcus CL, Omlin KJ, Basinki DJ, et al. Normal polysomnographic values for children and adolescents. Am Rev Respir Dis. 1992;146(5 Pt 1):1235-1239.
Flores-Fenlon N, Wright N, Lew C, et al. Retrospective analysis of inpatient polysomnogram characteristics and discharge outcomes in infants with bronchopulmonary dysplasia requiring home oxygen therapy. Pediatr Pulmonol. 2021;56(1):88-96.
Ortiz LE, McGrath-Morrow SA, Sterni LM, Collaco JM. Sleep disordered breathing in bronchopulmonary dysplasia. Pediatr Pulmonol. 2017;52(12):1583-1591.
Katz-Salamon M, Jonsson B, Lagercrantz H. Blunted peripheral chemoreceptor response to hyperoxia in a group of infants with bronchopulmonary dysplasia. Pediatr Pulmonol. 1995;20(2):101-106.
Paavonen EJ, Strang-Karlsson S, Räikkönen K, et al. Very low birth weight increases risk for sleep-disordered breathing in young adulthood: the Helsinki study of very low birth weight adults. Pediatrics. 2007;120(4):778-784.
Wellington G, Campbell A, Elder D. Intermittent hypoxia in preterm infants: measurement using the desaturation index. Pediatr Pulmonol. 2019;54(6):865-872.
Iber C, Ancoli-Israel S, Chesson A, Quan SF, eds. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. 1st ed. American Academy of Sleep Medicine; 2007:46.
Van Eyck A, Van Hoorenbeeck K, De Winter BY, Van Gaal L, De Backer W, Verhulst SL. Sleep disordered breathing and autonomic function in overweight and obese children and adolescents. ERJ Open Res. 2016;2(4):00038-02016.
O'Brien LM, Mervis CB, Holbrook CR, et al. Neurobehavioral implications of habitual snoring in children. Pediatrics. 2004;114(1):44-49.
Yeh J, McGrath-Morrow SA, Collaco JM. Oxygen weaning after hospital discharge in children with bronchopulmonary dysplasia. Pediatr Pulmonol. 2016;51(11):1206-1211.
Saletti A, Stick S, Dohert D, Simmer K. Home oxygen therapy after preterm birth in Western Austrailia. J Paediatr Child Health. 2004;40:519-523.
Dawson SK, D'Andrea LA, Lau R, Lagatta JM. Using a home oxygen weaning protocol and pCO2 to evaluate outcomes for infants with bronchopulmonary dysplasia discharged on home oxygen. Pediatr Pulmonol. 2020;55(12):3293-3303.
Rhein L, White H, Simoneau T, et al. Transmitted home oximetry and duration of home oxygen in premature infants. Pediatrics. 2020;146(2):e20200079.