Portable NMR for quantification of breast density in vivo: Proof-of-concept measurements and comparison with quantitative MRI.

Breast Density Breast Neoplasms / diagnostic imaging Female Humans Magnetic Resonance Imaging / methods Magnetic Resonance Spectroscopy Mammography Water
Breast cancer Breast density Compositional imaging Mammographic density Quantitative magnetic resonance imaging (MRI) Single-sided portable NMR

Journal

Magnetic resonance imaging
ISSN: 1873-5894
Titre abrégé: Magn Reson Imaging
Pays: Netherlands
ID NLM: 8214883

Informations de publication

Date de publication:
10 2022
Historique:
received: 22 03 2022
revised: 17 06 2022
accepted: 11 07 2022
pubmed: 18 7 2022
medline: 5 8 2022
entrez: 17 7 2022
Statut: ppublish

Résumé

Mammographic Density (MD) is the degree of radio-opacity of the breast in an X-ray mammogram. It is determined by the Fibroglandular: Adipose tissue ratio. MD has major implications in breast cancer risk and breast cancer chemoprevention. This study aimed to investigate the feasibility of accurate, low-cost quantification of MD in vivo without ionising radiation. We used single-sided portable nuclear magnetic resonance ("Portable NMR") due to its low cost and the absence of radiation-related safety concerns. Fifteen (N = 15) healthy female volunteers were selected for the study and underwent an imaging routine consisting of 2D X-ray mammography, quantitative breast 3T MRI (Dixon and T

Identifiants

DOI: 10.1016/j.mri.2022.07.004 PMID: 35843446
pubmed: 35843446
pii: S0730-725X(22)00114-X
doi: 10.1016/j.mri.2022.07.004
pii:
doi:

Substances chimiques

Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

212-223

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Nicholas D McKay-Parry (ND)

Department of Medical Imaging, Gold Coast University Hospital, Southport, QLD 4215, Australia.

Tony Blick (T)

School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, QLD 4006, Australia; Translational Research Institute, Woolloongabba, QLD 4102, Australia.

Satcha Foongkajornkiat (S)

School of Chemistry and Physics, Queensland University of Technology (QUT), Brisbane, QLD 4001, Australia.

Thomas Lloyd (T)

Department of Radiology, The Princess Alexandra Hospital, Woolloongabba, QLD 4102, Australia.

Erik W Thompson (EW)

School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, QLD 4006, Australia; Translational Research Institute, Woolloongabba, QLD 4102, Australia.

Honor J Hugo (HJ)

School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, QLD 4006, Australia; Translational Research Institute, Woolloongabba, QLD 4102, Australia; School of Health and Behavioural Sciences, University of the Sunshine Coast, Sippy Downs, QLD 4556, Australia; School of Medicine and Dentistry, Griffith University, Birtinya, QLD 4575, Australia.

Konstantin I Momot (KI)

School of Chemistry and Physics, Queensland University of Technology (QUT), Brisbane, QLD 4001, Australia. Electronic address: k.momot@qut.edu.au.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Densité mammaire › Portable NMR for quantification of breast...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Portable NMR for quantification of breast...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Portable NMR for quantification of breast...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Portable NMR for quantification of breast...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Portable NMR for quantification of breast...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Radiographie › Mammographie › Portable NMR for quantification of breast...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Portable NMR for quantification of breast...