Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance.

Animals Calcineurin / genetics Calcineurin Inhibitors Heterozygote Male Mice Muscle Fatigue Muscle, Skeletal / metabolism Neurogranin / genetics Tenotomy
Calcineurin Calmodulin NFAT Oxidative fibre Unloading

Journal

Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516

Informations de publication

Date de publication:
01 10 2022
Historique:
received: 11 07 2022
revised: 14 07 2022
accepted: 15 07 2022
pubmed: 26 7 2022
medline: 24 8 2022
entrez: 25 7 2022
Statut: ppublish

Résumé

Neurogranin (Ng) is a calmodulin (CaM) binding protein that negatively regulates calcineurin - a Ca

Identifiants

DOI: 10.1016/j.bbrc.2022.07.062 PMID: 35878428
pubmed: 35878428
pii: S0006-291X(22)01037-3
doi: 10.1016/j.bbrc.2022.07.062
pii:
doi:

Substances chimiques

Calcineurin Inhibitors 0
Nrgn protein, mouse 0
Neurogranin 132654-77-4
Calcineurin EC 3.1.3.16

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

89-95

Subventions

Organisme : CIHR
Pays : Canada

Informations de copyright

Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare no competing or financial interests.

Auteurs

Ryan W Baranowski (RW)

Centre for Bone and Muscle Health, Brock University, St. Catharines, ON, L2S 3A1, Canada; Department of Kinesiology, Brock University, St. Catharines, ON, L2S 3A1, Canada.

Jessica L Braun (JL)

Centre for Bone and Muscle Health, Brock University, St. Catharines, ON, L2S 3A1, Canada; Department of Kinesiology, Brock University, St. Catharines, ON, L2S 3A1, Canada.

Rene Vandenboom (R)

Centre for Bone and Muscle Health, Brock University, St. Catharines, ON, L2S 3A1, Canada; Department of Kinesiology, Brock University, St. Catharines, ON, L2S 3A1, Canada.

Val A Fajardo (VA)

Centre for Bone and Muscle Health, Brock University, St. Catharines, ON, L2S 3A1, Canada; Department of Kinesiology, Brock University, St. Catharines, ON, L2S 3A1, Canada. Electronic address: vfajardo@brocku.ca.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Phosphoprotein Phosphatases › Calcineurine › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de la calcineurine › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Hétérozygote › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Fatigue musculaire › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Muscles squelettiques › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neurogranine › Neurogranin inhibits calcineurin in murine...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures orthopédiques › Ténotomie › Neurogranin inhibits calcineurin in murine...