Evaluating Peptide Fragment Ion Detection Using Traveling Wave Ion Mobility Spectrometry with Signal-Enhanced MS

Ion Mobility Spectrometry / methods Ions Peptide Fragments Peptides / chemistry Tandem Mass Spectrometry / methods

Journal

Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536

Informations de publication

Date de publication:
09 08 2022
Historique:
pubmed: 30 7 2022
medline: 11 8 2022
entrez: 29 7 2022
Statut: ppublish

Résumé

The inherent poor sampling of fragment ions in time-of-flight mass analyzers was recently improved for data-dependent acquisition (DDA) by considering their drift times in traveling wave ion mobility spectrometry (TWIMS). Here, we extend this TWIMS-DDA approach to the data-independent acquisition (DIA) mode MS

Identifiants

DOI: 10.1021/acs.analchem.2c00461 PMID: 35904512
pubmed: 35904512
doi: 10.1021/acs.analchem.2c00461
doi:

Substances chimiques

Ions 0
Peptide Fragments 0
Peptides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10930-10941

Auteurs

Juan Camilo Rojas Echeverri (JC)

Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, 04103 Leipzig, Germany.
Center for Biotechnology and Biomedicine, Universität Leipzig, 04103 Leipzig, Germany.
ORCID: 0000-0003-4440-9580

Daniela Volke (D)

Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, 04103 Leipzig, Germany.
Center for Biotechnology and Biomedicine, Universität Leipzig, 04103 Leipzig, Germany.

Sanja Milkovska-Stamenova (S)

Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, 04103 Leipzig, Germany.
Center for Biotechnology and Biomedicine, Universität Leipzig, 04103 Leipzig, Germany.

Ralf Hoffmann (R)

Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, 04103 Leipzig, Germany.
Center for Biotechnology and Biomedicine, Universität Leipzig, 04103 Leipzig, Germany.
ORCID: 0000-0001-9932-5646

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrométrie de mobilité ionique › Evaluating Peptide Fragment Ion Detection...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Evaluating Peptide Fragment Ion Detection...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Fragments peptidiques › Evaluating Peptide Fragment Ion Detection...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Evaluating Peptide Fragment Ion Detection...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › Evaluating Peptide Fragment Ion Detection...