Neurological pupil index and its association with other prognostic tools after cardiac arrest: A post hoc analysis.
Automated pupillometer
Automated pupillometry
Brain injury
Concordance
Heart arrest
Prognosis
Journal
Resuscitation
ISSN: 1873-1570
Titre abrégé: Resuscitation
Pays: Ireland
ID NLM: 0332173
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
30
05
2022
revised:
18
07
2022
accepted:
23
07
2022
pubmed:
2
8
2022
medline:
5
10
2022
entrez:
1
8
2022
Statut:
ppublish
Résumé
We evaluated the concordance of the Neurological pupil Index (NPi) with other predictors of outcome after cardiac arrest (CA). Post hoc analysis of a prospective, international, multicenter study including adult CA patients. Predictors of unfavorable outcome (UO, Cerebral Performance Category of 3-5 at 3 months) included: a) worst NPi ≤ 2; b) presence of discontinuous encephalography (EEG) background; c) bilateral absence of N20 waves on somatosensory evoked potentials (N20 A total of 269/456 (59 %) patients had UO and 186 (41 %) underwent MMM. The presence of myoclonus was assessed in all patients, EEG in 358 (78 %), N20 in 186 (41 %) and NSE measurement in 228 (50 %). Patients with discontinuous EEG, N20 In this study, NPi ≤ 2 had moderate to high concordance with other unfavorable outcome prognosticators of hypoxic-ischemic brain injury. This indicates that NPi measurement could be considered as a valid tool for coma prognostication after cardiac arrest.
Identifiants
pubmed: 35914656
pii: S0300-9572(22)00621-9
doi: 10.1016/j.resuscitation.2022.07.030
pii:
doi:
Substances chimiques
Phosphopyruvate Hydratase
EC 4.2.1.11
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
259-266Informations de copyright
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