The effect of cladribine tablets in people with more active multiple sclerosis: a plain language summary.
CLARITY
cladribine tablets
clinical trial
lay summary
multiple sclerosis
plain language summary
relapses
treatment options
Journal
Neurodegenerative disease management
ISSN: 1758-2032
Titre abrégé: Neurodegener Dis Manag
Pays: England
ID NLM: 101517977
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
pubmed:
4
8
2022
medline:
27
10
2022
entrez:
3
8
2022
Statut:
ppublish
Résumé
This article summarizes the findings from a previously published article in Researchers found that in people with more active MS, treatment with cladribine tablets led to a lower risk of relapse and there were more people who had no relapses. People also had a lower chance of their MS worsening and had fewer new lesions in the brain. These benefits were seen regardless of whether the participants had prior treatment. Researchers concluded that in these people with more active MS, treatment with cladribine tablets led to better outcomes over 2 years compared with treatment with placebo tablets, regardless of whether the participants had taken any prior MS treatments.
Identifiants
pubmed: 35920065
doi: 10.2217/nmt-2022-0009
doi:
Substances chimiques
Cladribine
47M74X9YT5
Immunosuppressive Agents
0
Tablets
0
Banques de données
ClinicalTrials.gov
['NCT00213135']
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM