Causes of Death in Endovascularly Treated Patients with Acute Stroke.


Journal

AJNR. American journal of neuroradiology
ISSN: 1936-959X
Titre abrégé: AJNR Am J Neuroradiol
Pays: United States
ID NLM: 8003708

Informations de publication

Date de publication:
09 2022
Historique:
received: 13 03 2022
accepted: 17 06 2022
pubmed: 12 8 2022
medline: 30 12 2022
entrez: 11 8 2022
Statut: ppublish

Résumé

Because stroke therapy has changed with the introduction of endovascular stroke treatment as a standard approach, studies on intrahospital causes of death from stroke are no longer up-to-date. The purpose of this observational study was to present the causes of death during hospitalization of patients with ischemic stroke who received endovascular stroke treatment, with the focus on a differentiation of curative and secondary palliative treatment. We studied a total cohort of 1342 patients who received endovascular stroke treatment in a tertiary stroke center (Aachen, Germany) between 2010 and 2020 and analyzed the causes of death in all 326 consecutive deceased patients. We distinguished between curative treatment and a secondary palliative approach and analyzed causes of death and treatment numbers across the years. In the entire cohort of 326 deceased patients, the most common cause of death was of a cerebrovascular nature (51.5%), followed by pneumonia and sepsis (25.8%) and cardiovascular causes (8.3%). Neurovascular causes constituted 75.8% of reasons for palliation. In the group with a secondary palliative approach, causes of death were neurovascular in 54.0% of patients and pneumonia and sepsis in 26.0% of patients. Cerebrovascular causes in patients with stroke play a major role in the intrahospital causes of death and reasons for palliation. Considering the large proportion of secondarily palliative-treated patients, reasons for palliation should be considered instead of causes of death to avoid concealment by, for example, life-terminating measures.

Sections du résumé

BACKGROUND AND PURPOSE
Because stroke therapy has changed with the introduction of endovascular stroke treatment as a standard approach, studies on intrahospital causes of death from stroke are no longer up-to-date. The purpose of this observational study was to present the causes of death during hospitalization of patients with ischemic stroke who received endovascular stroke treatment, with the focus on a differentiation of curative and secondary palliative treatment.
MATERIALS AND METHODS
We studied a total cohort of 1342 patients who received endovascular stroke treatment in a tertiary stroke center (Aachen, Germany) between 2010 and 2020 and analyzed the causes of death in all 326 consecutive deceased patients. We distinguished between curative treatment and a secondary palliative approach and analyzed causes of death and treatment numbers across the years.
RESULTS
In the entire cohort of 326 deceased patients, the most common cause of death was of a cerebrovascular nature (51.5%), followed by pneumonia and sepsis (25.8%) and cardiovascular causes (8.3%). Neurovascular causes constituted 75.8% of reasons for palliation. In the group with a secondary palliative approach, causes of death were neurovascular in 54.0% of patients and pneumonia and sepsis in 26.0% of patients.
CONCLUSIONS
Cerebrovascular causes in patients with stroke play a major role in the intrahospital causes of death and reasons for palliation. Considering the large proportion of secondarily palliative-treated patients, reasons for palliation should be considered instead of causes of death to avoid concealment by, for example, life-terminating measures.

Identifiants

pubmed: 35953279
pii: ajnr.A7599
doi: 10.3174/ajnr.A7599
pmc: PMC9451643
doi:

Types de publication

Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1299-1303

Informations de copyright

© 2022 by American Journal of Neuroradiology.

Auteurs

H Nagel (H)

From the Departments of Neuroradiology (H.N., D.H., H.R., M.W., O.N.).

J Pinho (J)

Neurology (J.P., P.H., J.B.S., A.R.), University Hospital RWTH, Aachen, Germany.

D Hasan (D)

From the Departments of Neuroradiology (H.N., D.H., H.R., M.W., O.N.).

H Ridwan (H)

From the Departments of Neuroradiology (H.N., D.H., H.R., M.W., O.N.).

P Habib (P)

Neurology (J.P., P.H., J.B.S., A.R.), University Hospital RWTH, Aachen, Germany.

J B Schulz (JB)

Neurology (J.P., P.H., J.B.S., A.R.), University Hospital RWTH, Aachen, Germany.

M Wiesmann (M)

From the Departments of Neuroradiology (H.N., D.H., H.R., M.W., O.N.).

A Reich (A)

Neurology (J.P., P.H., J.B.S., A.R.), University Hospital RWTH, Aachen, Germany.

O Nikoubashman (O)

From the Departments of Neuroradiology (H.N., D.H., H.R., M.W., O.N.) onikoubashman@ukaachen.de.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH