Long-term outcome of tibial plateau leveling osteotomy using an antimicrobial silver-based coated plate in dogs.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2022
2022
Historique:
received:
18
04
2022
accepted:
21
07
2022
entrez:
12
8
2022
pubmed:
13
8
2022
medline:
17
8
2022
Statut:
epublish
Résumé
To evaluate long-term outcome using the BioMedtrix™ TPLO Curve® plate in dogs with cranial cruciate ligament disease (CrCLd) treated by tibial plateau leveling osteotomy (TPLO). Retrospective case study. Dogs (n = 323, 337 stifles). Medical records were searched for dogs presented with CrCLd and treated by TPLO with the BioMedtrix™ TPLO Curve® plate for 3.5 mm screws between March 2018 and December 2020. Tibial plateau angles (TPA) were measured on preoperative, postoperative, and follow-up radiographs. Changes in TPA between postoperative and follow-up radiographs (ModTPA) were calculated. Radiographic bone healing was scored. Complications were evaluated. Surgical site infections (SSI) were compared to a control group of dogs treated with the Synthes™ TPLO plate between January and December 2017. Owners of both groups were contacted by telephone at least 1 year postoperatively. The BioMedtrix™ group was composed of 237 dogs (248 stifles), the control group was composed of 86 dogs (89 stifles). In the BioMedtrix™ group, radiographic follow-up was performed at a median of 48 days. Average ModTPA was 1.2°. Bone healing was graded as complete, good, poor, and none in 18%, 62%, 20%, and 0%, respectively. At a median of 786 days postoperatively, minor and major postoperative complications were observed in 6 (2.4%) and 32 (12.9%) cases in this group, respectively. During the first year following the surgery, 23 (9.3%) and 12 (13.5%) cases suffered a SSI, of which 12 (4.8%) and 7 (7.9%) had their implant explanted in the BioMedtrix™ group and the control group, respectively. There was no significant difference between groups for SSI and implant explantations (p = 0.31 and p = 0.29, respectively). The BioMedtrix™ TPLO Curve® plate provided a reliable fixation system for osteotomy healing after TPLO. Bone healing and long-term complication rates were similar to previous studies using other implants. SSI rates were similar between the BioMedtrix™ group and the control group. The antimicrobial HyProtect® coating of the plate did not reduce SSI in this study. The BioMedtrix™ TPLO Curve® plate can be safely used for TPLO. The value of the antimicrobial HyProtect® coating of the plate may be questioned, as SSI rate was not lower in this study compared to the control group or previous reports.
Identifiants
pubmed: 35960740
doi: 10.1371/journal.pone.0272555
pii: PONE-D-22-10523
pmc: PMC9374240
doi:
Substances chimiques
Anti-Infective Agents
0
Silver
3M4G523W1G
Banques de données
figshare
['10.6084/m9.figshare.20379918', '10.6084/m9.figshare.20379921']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0272555Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Vet Surg. 2018 May;47(4):481-489
pubmed: 29878479
Vet Surg. 2008 Jun;37(4):357-65
pubmed: 18564260
Vet Surg. 2010 Jun;39(4):475-81
pubmed: 20345527
Vet Comp Orthop Traumatol. 2012;25(5):349-58
pubmed: 22534675
Vet Surg. 2008 Apr;37(3):300-5
pubmed: 18394079
Vet Surg. 2020 Jan;49(1):106-113
pubmed: 31664725
Vet Comp Orthop Traumatol. 2019 Jan;32(1):18-25
pubmed: 30646408
Biomaterials. 2013 Nov;34(34):8533-54
pubmed: 23953781
Vet Clin North Am Small Anim Pract. 1993 Jul;23(4):777-95
pubmed: 8337790
Am J Infect Control. 1999 Apr;27(2):97-132; quiz 133-4; discussion 96
pubmed: 10196487
Vet Surg. 2010 Dec;39(8):905-8
pubmed: 21133952
Vet Surg. 2010 Jun;39(4):460-74
pubmed: 20345526
Vet Comp Orthop Traumatol. 2007;20(1):24-8
pubmed: 17364092
Vet Surg. 2021 May;50(4):729-739
pubmed: 33709459
Vet Surg. 2021 Jul;50(5):999-1008
pubmed: 33826172
Vet Surg. 2013 Oct;42(7):847-52
pubmed: 24033720
Vet Surg. 2010 Feb;39(2):187-94
pubmed: 20210966
Vet Surg. 2011 Feb;40(2):171-82
pubmed: 21223316
Vet Surg. 2018 Jun;47(S1):O6-O14
pubmed: 29135038
J Surg Oncol. 2010 Apr 1;101(5):389-95
pubmed: 20119985
J Am Vet Med Assoc. 2008 Jun 15;232(12):1818-24
pubmed: 18598150
Vet Surg. 2008 Jun;37(4):366-73
pubmed: 18564261
Vet Comp Orthop Traumatol. 2013;26(4):266-70
pubmed: 23613016
Vet Surg. 2018 Jul;47(5):634-639
pubmed: 30129067
Vet Surg. 2005 Jul-Aug;34(4):332-6
pubmed: 16212587
Vet Surg. 2009 Jan;38(1):40-8
pubmed: 19152616
Vet Surg. 2018 Jan;47(1):60-65
pubmed: 29144538
Appl Biochem Biotechnol. 2017 Dec;183(4):1351-1361
pubmed: 28573605
Vet Surg. 2020 Jul;49(5):930-939
pubmed: 32359005
Vet Surg. 2011 Oct;40(7):830-8
pubmed: 21906096
J Am Vet Med Assoc. 2018 Sep 1;253(5):586-597
pubmed: 30110219
Vet Surg. 2018 Nov;47(8):E79-E87
pubmed: 30267441
Vet Surg. 2006 Apr;35(3):294-9
pubmed: 16635011
Vet Surg. 2013 Aug;42(6):739-50
pubmed: 23889810
Vet Surg. 2012 Nov;41(8):931-7
pubmed: 23163286
Vet Surg. 2018 Oct;47(7):923-931
pubmed: 30239027
Chem Rev. 2013 Jul 10;113(7):4708-54
pubmed: 23488929
Can Vet J. 2014 Mar;55(3):249-54
pubmed: 24587508
Vet Comp Orthop Traumatol. 2016 Jul 19;29(4):347-50
pubmed: 27102292