Post-mortem investigation into a death involving doping agents: The case of a body builder.
Journal
Drug testing and analysis
ISSN: 1942-7611
Titre abrégé: Drug Test Anal
Pays: England
ID NLM: 101483449
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
25
07
2022
received:
21
04
2022
accepted:
25
07
2022
pubmed:
15
8
2022
medline:
12
10
2022
entrez:
14
8
2022
Statut:
ppublish
Résumé
A young male was found dead on the bed of a hotel room. He was expected to take part in a bodybuilding competition the day after. During the site inspection, drugs of different types were found. The next day, an autopsy was performed. The evidence of cardiomegaly with organ congestion involving lung, liver, kidneys, adrenal glands, spleen and brain was confirmed by both the autoptic and the histopathological exam. However, the cause of death needed to be investigated. A thorough toxicological investigation was undertaken by gas chromatography-mass spectrometry (GC-MS), liquid chromatography-high resolution mass spectrometry (LC-HRMS) and liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) on samples of urine, blood and hair. Clenbuterol, a long-acting selective beta Hair analysis has proven to be crucial in identifying drug misuse and the contributing cause of death.
Identifiants
pubmed: 35964965
doi: 10.1002/dta.3350
pmc: PMC9804486
doi:
Substances chimiques
Anabolic Agents
0
Testosterone Congeners
0
Epitestosterone
481-30-1
Androsterone
C24W7J5D5R
Clenbuterol
XTZ6AXU7KN
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
1795-1799Informations de copyright
© 2022 The Authors. Drug Testing and Analysis published by John Wiley & Sons Ltd.
Références
Food Addit Contam. 2005 Jun;22(6):563-6
pubmed: 16019830
J Anal Toxicol. 2019 Sep 10;43(8):660-665
pubmed: 31436794
Basic Clin Pharmacol Toxicol. 2018 Aug;123(2):182-187
pubmed: 29498199
Curr Neuropharmacol. 2015 Jan;13(1):101-21
pubmed: 26074746
Clin Cardiol. 1996 Feb;19(2):153-5
pubmed: 8821428
Scand J Med Sci Sports. 2018 Oct;28(10):2114-2122
pubmed: 29777633
Med Sci Sports Exerc. 1995 Aug;27(8):1118-21
pubmed: 7476054
Eur J Cardiovasc Prev Rehabil. 2006 Oct;13(5):687-94
pubmed: 17001206
J Emerg Med. 2016 Sep;51(3):259-61
pubmed: 27431866
Ann Cardiol Angeiol (Paris). 2018 Nov;67(5):365-369
pubmed: 30290907
J Anal Toxicol. 2008 Sep;32(7):522-8
pubmed: 18713522
J Emerg Med. 2013 Feb;44(2):444-9
pubmed: 22633759
J Anal Toxicol. 2019 May 1;43(4):307-315
pubmed: 30561666
J Intern Med. 2019 Mar;285(3):333-340
pubmed: 30460728
South Med J. 1998 Aug;91(8):780-4
pubmed: 9715231
J Med Toxicol. 2007 Jun;3(2):56-60
pubmed: 18072161
Drug Test Anal. 2022 Oct;14(10):1795-1799
pubmed: 35964965
Drug Test Anal. 2020 Oct;12(10):1419-1431
pubmed: 32578357
Am J Mens Health. 2018 Sep;12(5):1700-1704
pubmed: 29926766