SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
19 08 2022
Historique:
received: 06 06 2022
accepted: 26 07 2022
entrez: 19 8 2022
pubmed: 20 8 2022
medline: 24 8 2022
Statut: epublish

Résumé

Efforts to cure HIV have focused on reactivating latent proviruses to enable elimination by CD8

Identifiants

pubmed: 35985993
doi: 10.1038/s41467-022-32376-z
pii: 10.1038/s41467-022-32376-z
pmc: PMC9389512
doi:

Substances chimiques

COVID-19 Vaccines 0
RNA, Messenger 0
Vaccines, Synthetic 0
mRNA Vaccines 0
nef Gene Products, Human Immunodeficiency Virus 0
nef protein, Human immunodeficiency virus 1 0
nef protein, Human immunodeficiency virus 2 0
Granzymes EC 3.4.21.-
BNT162 Vaccine N38TVC63NU

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

4888

Subventions

Organisme : NIAID NIH HHS
ID : UM1 AI164565
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI162221
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI170245
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002384
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI150398
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001866
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI126617
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI131798
Pays : United States

Informations de copyright

© 2022. The Author(s).

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Auteurs

Eva M Stevenson (EM)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Sandra Terry (S)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Dennis Copertino (D)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Louise Leyre (L)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.

Ali Danesh (A)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Jared Weiler (J)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Adam R Ward (AR)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Pragya Khadka (P)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Evan McNeil (E)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Kevin Bernard (K)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Itzayana G Miller (IG)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Grant B Ellsworth (GB)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Carrie D Johnston (CD)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Eli J Finkelsztein (EJ)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Paul Zumbo (P)

Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA.

Doron Betel (D)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA.

Friederike Dündar (F)

Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA.
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA.

Maggie C Duncan (MC)

Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.

Hope R Lapointe (HR)

British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.

Sarah Speckmaier (S)

British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.

Nadia Moran-Garcia (N)

British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.

Michelle Premazzi Papa (MP)

Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

Samuel Nicholes (S)

Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

Carissa J Stover (CJ)

Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

Rebecca M Lynch (RM)

Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

Marina Caskey (M)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA.

Christian Gaebler (C)

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA.

Tae-Wook Chun (TW)

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases (NIAID, NIH, Bethesda, MD, USA.

Alberto Bosque (A)

Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

Timothy J Wilkin (TJ)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Guinevere Q Lee (GQ)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Zabrina L Brumme (ZL)

Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.

R Brad Jones (RB)

Department of Medicine, Weill Cornell Medical College, New York, NY, USA. rbjones@med.cornell.edu.
Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA. rbjones@med.cornell.edu.

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Classifications MeSH