Affinity Assays for Cannabinoids Detection: Are They Amenable to On-Site Screening?
affinity biosensor
cannabidiol
on-site detection
roadside testing
tetrahydrocannabinol
Journal
Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191
Informations de publication
Date de publication:
06 Aug 2022
06 Aug 2022
Historique:
received:
05
07
2022
revised:
27
07
2022
accepted:
04
08
2022
entrez:
25
8
2022
pubmed:
26
8
2022
medline:
27
8
2022
Statut:
epublish
Résumé
Roadside testing of illicit drugs such as tetrahydrocannabinol (THC) requires simple, rapid, and cost-effective methods. The need for non-invasive detection tools has led to the development of selective and sensitive platforms, able to detect phyto- and synthetic cannabinoids by means of their main metabolites in breath, saliva, and urine samples. One may estimate the time passed from drug exposure and the frequency of use by corroborating the detection results with pharmacokinetic data. In this review, we report on the current detection methods of cannabinoids in biofluids. Fluorescent, electrochemical, colorimetric, and magnetoresistive biosensors will be briefly overviewed, putting emphasis on the affinity formats amenable to on-site screening, with possible applications in roadside testing and anti-doping control.
Identifiants
pubmed: 36005003
pii: bios12080608
doi: 10.3390/bios12080608
pmc: PMC9405638
pii:
doi:
Substances chimiques
Cannabinoids
0
Dronabinol
7J8897W37S
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Romanian Ministry of Research, Innovation and Digitization, CNCS/CCCDI - UEFISCDI
ID : PN-III-P4-ID-PCE2020-0998
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