A microbial supply chain for production of the anti-cancer drug vinblastine.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
12
04
2021
accepted:
27
07
2022
pubmed:
1
9
2022
medline:
11
9
2022
entrez:
31
8
2022
Statut:
ppublish
Résumé
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine
Identifiants
pubmed: 36045295
doi: 10.1038/s41586-022-05157-3
pii: 10.1038/s41586-022-05157-3
pmc: PMC9452304
doi:
Substances chimiques
Antineoplastic Agents
0
Polyisoprenyl Phosphates
0
Vinca Alkaloids
0
Vinblastine
5V9KLZ54CY
geranyl pyrophosphate
763-10-0
Tryptophan
8DUH1N11BX
catharanthine
WT0YJV846J
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
341-347Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022. The Author(s).
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