Removal of cardiac AL amyloid with positive remodelling of cardiomyocytes and of restrictive cardiomyopathy.
Cardiac AL amyloid
Remodelling
Restrictive cardiomyopathy
Journal
ESC heart failure
ISSN: 2055-5822
Titre abrégé: ESC Heart Fail
Pays: England
ID NLM: 101669191
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
revised:
01
06
2022
received:
18
01
2022
accepted:
03
06
2022
pubmed:
4
9
2022
medline:
24
12
2022
entrez:
3
9
2022
Statut:
ppublish
Résumé
Herein, we describe histological mobilization of light chain cardiac amyloid documented by sequential left ventricular endomyocardial biopsies. These findings were associated with positive remodelling of cardiomyocytes and of restrictive cardiomyopathy resulting from 14 courses of chemotherapy over 17 years of time. Histological and ultrastructural findings of light chain cardiac amyloid removal led to increase in cardiomyocyte dimension and electrocardiogram voltages, reduction of biventricular wall thickness with improvement of left ventricular diastolic function, and NYHA class shifting from III to I.
Identifiants
pubmed: 36056647
doi: 10.1002/ehf2.14017
pmc: PMC9773750
doi:
Substances chimiques
Amyloid
0
Types de publication
Case Reports
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4330-4334Informations de copyright
© 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.
Références
JACC Cardiovasc Imaging. 2014 Mar;7(3):254-63
pubmed: 24560214
N Engl J Med. 1980 Jun 5;302(23):1283-92
pubmed: 6154243
ESC Heart Fail. 2022 Dec;9(6):4330-4334
pubmed: 36056647
JACC CardioOncol. 2019 Sep 24;1(1):117-130
pubmed: 34396169
Circulation. 1997 Aug 19;96(4):1180-4
pubmed: 9286947
Circulation. 2007 Nov 6;116(19):2216-33
pubmed: 17959655
N Engl J Med. 1980 Jun 12;302(24):1333-43
pubmed: 6990257
Eur J Heart Fail. 2021 Jun;23(6):854-871
pubmed: 34010472