Toward learning the principles of plant gene regulation.

DNA motifs DNA regulatory code deep neural networks gene expression prediction gene regulatory structure machine learning

Journal

Trends in plant science
ISSN: 1878-4372
Titre abrégé: Trends Plant Sci
Pays: England
ID NLM: 9890299

Informations de publication

Date de publication:
12 2022
Historique:
received: 09 04 2022
revised: 09 08 2022
accepted: 17 08 2022
pubmed: 14 9 2022
medline: 15 11 2022
entrez: 13 9 2022
Statut: ppublish

Résumé

Advanced machine learning (ML) algorithms produce highly accurate models of gene expression, uncovering novel regulatory features in nucleotide sequences involving multiple cis-regulatory regions across whole genes and structural properties. These broaden our understanding of gene regulation and point to new principles to test and adopt in the field of plant science.

Identifiants

pubmed: 36100536
pii: S1360-1385(22)00216-3
doi: 10.1016/j.tplants.2022.08.010
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1206-1208

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared.

Auteurs

Jan Zrimec (J)

Department of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia. Electronic address: jan.zrimec@nib.si.

Aleksej Zelezniak (A)

Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, 412 96, Gothenburg, Sweden.

Kristina Gruden (K)

Department of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia. Electronic address: kristina.gruden@nib.si.

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Classifications MeSH