Clinical outcomes of adults and children with cystic fibrosis during the COVID-19 pandemic.
COVID-19
Cystic fibrosis
Telehealth
Journal
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
ISSN: 1873-5010
Titre abrégé: J Cyst Fibros
Pays: Netherlands
ID NLM: 101128966
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
19
04
2022
revised:
06
09
2022
accepted:
14
09
2022
medline:
12
6
2023
pubmed:
27
9
2022
entrez:
26
9
2022
Statut:
ppublish
Résumé
The onset of the COVID-19 pandemic was associated with restricted community movement and limited access to healthcare facilities, resulting in changed clinical service delivery to people with cystic fibrosis (CF). This study aimed to determine clinical outcomes of Australian adults and children with CF in the 12-months following the onset of the COVID-19 pandemic. This longitudinal cohort study used national registry data. Primary outcomes were 12-month change in percent predicted forced expiratory volume in one second (FEV1 %pred), body mass index (BMI) in adults and BMI z-scores in children. A piecewise linear mixed-effects model was used to determine trends in outcomes before and after pandemic onset. Data were available for 3662 individuals (median age 19.6 years, range 0-82). When trends in outcomes before and after pandemic onset were compared; FEV1 %pred went from a mean annual decline of -0.13% (95%CI -0.36 to 0.11) to a mean improvement of 1.76% (95%CI 1.46-2.05). Annual trend in BMI improved from 0.03 kg/m In the 12-months following the onset of the COVID-19 pandemic, there was an improvement in the clinical outcomes of people with CF when compared to the pre-pandemic period.
Sections du résumé
BACKGROUND
BACKGROUND
The onset of the COVID-19 pandemic was associated with restricted community movement and limited access to healthcare facilities, resulting in changed clinical service delivery to people with cystic fibrosis (CF). This study aimed to determine clinical outcomes of Australian adults and children with CF in the 12-months following the onset of the COVID-19 pandemic.
METHODS
METHODS
This longitudinal cohort study used national registry data. Primary outcomes were 12-month change in percent predicted forced expiratory volume in one second (FEV1 %pred), body mass index (BMI) in adults and BMI z-scores in children. A piecewise linear mixed-effects model was used to determine trends in outcomes before and after pandemic onset.
RESULTS
RESULTS
Data were available for 3662 individuals (median age 19.6 years, range 0-82). When trends in outcomes before and after pandemic onset were compared; FEV1 %pred went from a mean annual decline of -0.13% (95%CI -0.36 to 0.11) to a mean improvement of 1.76% (95%CI 1.46-2.05). Annual trend in BMI improved from 0.03 kg/m
CONCLUSION
CONCLUSIONS
In the 12-months following the onset of the COVID-19 pandemic, there was an improvement in the clinical outcomes of people with CF when compared to the pre-pandemic period.
Identifiants
pubmed: 36163166
pii: S1569-1993(22)00685-3
doi: 10.1016/j.jcf.2022.09.006
pmc: PMC9477965
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
581-586Informations de copyright
Copyright © 2022. Published by Elsevier B.V.
Références
Paediatr Respir Rev. 2016 Sep;20:55-66
pubmed: 27259460
J Cyst Fibros. 2011 Jun;10 Suppl 2:S75-8
pubmed: 21658646
Transp Policy (Oxf). 2020 Sep;96:76-93
pubmed: 32834680
PLoS One. 2021 Aug 3;16(8):e0255659
pubmed: 34343205
Pediatr Pulmonol. 2021 Sep;56(9):3065-3067
pubmed: 34265187
J Cyst Fibros. 2021 Dec;20 Suppl 3:31-38
pubmed: 34930540
Chest. 2022 May;161(5):1167-1179
pubmed: 34896356
Ann Am Thorac Soc. 2022 Mar;19(3):498-500
pubmed: 34406918
Paediatr Respir Rev. 2018 Mar;26:19-21
pubmed: 28416301
J Cyst Fibros. 2021 Jul;20(4):719-720
pubmed: 32873523
J Cyst Fibros. 2020 May;19(3):499-502
pubmed: 31735561
Allergy. 2021 Jun;76(6):1765-1775
pubmed: 33608919
Euro Surveill. 2020 Nov;25(47):
pubmed: 33243355
Pediatr Pulmonol. 2021 May;56(5):1271-1273
pubmed: 33434352
PLoS One. 2021 Sep 23;16(9):e0257852
pubmed: 34555108
J Patient Exp. 2021 Apr 22;8:23743735211008295
pubmed: 34179427
Pediatrics. 2021 Jul;148(1):
pubmed: 33632935
J Telemed Telecare. 2017 Aug;23(7):673-679
pubmed: 27444187
J Cyst Fibros. 2021 May;20(3):e23-e28
pubmed: 33775604
Nutrients. 2020 Jun 23;12(6):
pubmed: 32585830
Clin Nutr. 2002 Apr;21(2):141-4
pubmed: 12056786
Eur Respir J. 2012 Jul;40(1):61-6
pubmed: 22135280
Eur Respir J. 2012 Aug;40(2):510-2
pubmed: 22855475
Int J Gen Med. 2020 Nov 17;13:1175-1186
pubmed: 33235489
J Cyst Fibros. 2014 May;13 Suppl 1:S3-22
pubmed: 24856776
J Cyst Fibros. 2021 Dec;20 Suppl 3:49-54
pubmed: 34930543
Paediatr Respir Rev. 2018 Mar;26:22-23
pubmed: 28366680