PD-1-cis IL-2R agonism yields better effectors from stem-like CD8


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
10 2022
Historique:
received: 14 03 2021
accepted: 04 08 2022
pubmed: 29 9 2022
medline: 12 10 2022
entrez: 28 9 2022
Statut: ppublish

Résumé

Expansion and differentiation of antigen-experienced PD-1

Identifiants

pubmed: 36171284
doi: 10.1038/s41586-022-05192-0
pii: 10.1038/s41586-022-05192-0
pmc: PMC9534752
doi:

Substances chimiques

Antibodies, Blocking 0
B7-H1 Antigen 0
Interleukin-2 0
Interleukin-2 Receptor alpha Subunit 0
Programmed Cell Death 1 Receptor 0
Receptors, Interleukin-2 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

161-172

Subventions

Organisme : NIH HHS
ID : P51 OD011132
Pays : United States
Organisme : NIH HHS
ID : S10 OD026799
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s).

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Auteurs

Laura Codarri Deak (L)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Valeria Nicolini (V)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Masao Hashimoto (M)

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.

Maria Karagianni (M)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Petra C Schwalie (PC)

Roche Innovation Center Basel, Basel, Switzerland.

Laura Lauener (L)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Eleni Maria Varypataki (EM)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Marine Richard (M)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Esther Bommer (E)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Johannes Sam (J)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Stefanie Joller (S)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Mario Perro (M)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Floriana Cremasco (F)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Leo Kunz (L)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Emilio Yanguez (E)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Tamara Hüsser (T)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Ramona Schlenker (R)

Roche Innovation Center Munich, Penzberg, Germany.

Marisa Mariani (M)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Vinko Tosevski (V)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Sylvia Herter (S)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Marina Bacac (M)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Inja Waldhauer (I)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Sara Colombetti (S)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Xavier Gueripel (X)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Stephan Wullschleger (S)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, EPFL, Lausanne, Switzerland.
Swiss Cancer Center Leman (SCCL), Lausanne, Switzerland.

Melanie Tichet (M)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, EPFL, Lausanne, Switzerland.
Swiss Cancer Center Leman (SCCL), Lausanne, Switzerland.
Ludwig Institute for Cancer Research, Lausanne Branch, Lausanne, Switzerland.
Agora Translational Cancer Research Center, Lausanne, Switzerland.

Douglas Hanahan (D)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, EPFL, Lausanne, Switzerland.
Swiss Cancer Center Leman (SCCL), Lausanne, Switzerland.
Ludwig Institute for Cancer Research, Lausanne Branch, Lausanne, Switzerland.
Agora Translational Cancer Research Center, Lausanne, Switzerland.

Haydn T Kissick (HT)

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.
Winship Cancer Institute of Emory University, Atlanta, GA, USA.

Stephane Leclair (S)

Roche Innovation Center Munich, Penzberg, Germany.

Anne Freimoser-Grundschober (A)

Roche Innovation Center Zurich, Schlieren, Switzerland.

Stefan Seeber (S)

Roche Innovation Center Munich, Penzberg, Germany.

Volker Teichgräber (V)

Roche Innovation Center Basel, Basel, Switzerland.

Rafi Ahmed (R)

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Winship Cancer Institute of Emory University, Atlanta, GA, USA.

Christian Klein (C)

Roche Innovation Center Zurich, Schlieren, Switzerland. christian.klein.ck1@roche.com.

Pablo Umaña (P)

Roche Innovation Center Zurich, Schlieren, Switzerland. pablo.umana@roche.com.

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