On the role of ubiquinone in the proton translocation mechanism of respiratory complex I.
energy conservation
mitochondria
oxidative phosphorylation
proton pumping
Journal
FEBS letters
ISSN: 1873-3468
Titre abrégé: FEBS Lett
Pays: England
ID NLM: 0155157
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
revised:
23
09
2022
received:
08
08
2022
accepted:
23
09
2022
pubmed:
2
10
2022
medline:
26
1
2023
entrez:
1
10
2022
Statut:
ppublish
Résumé
Complex I converts oxidoreduction energy into a proton electrochemical gradient across the inner mitochondrial or bacterial cell membrane. This gradient is the primary source of energy for aerobic synthesis of ATP. Oxidation of reduced nicotinamide adenine dinucleotide (NADH) by ubiquinone (Q) yields NAD
Identifiants
pubmed: 36180980
doi: 10.1002/1873-3468.14506
doi:
Substances chimiques
Ubiquinone
1339-63-5
Electron Transport Complex I
EC 7.1.1.2
Protons
0
NAD
0U46U6E8UK
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
224-236Subventions
Organisme : Academy of Finland
Organisme : Helsingin Yliopisto
Organisme : Jane ja Aatos Erkon Säätiö
Organisme : Magnus Ehrnroothin Säätiö
Organisme : Sigrid Juséliuksen Säätiö
Informations de copyright
© 2022 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
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