Neoepitopes prediction strategies: an integration of cancer genomics and immunoinformatics approaches.
cancer
genomics
integration
neoepitopes
predictions
strategies
Journal
Briefings in functional genomics
ISSN: 2041-2657
Titre abrégé: Brief Funct Genomics
Pays: England
ID NLM: 101528229
Informations de publication
Date de publication:
20 01 2023
20 01 2023
Historique:
received:
28
07
2022
revised:
28
09
2022
accepted:
14
10
2022
pubmed:
19
11
2022
medline:
24
1
2023
entrez:
18
11
2022
Statut:
ppublish
Résumé
A major near-term medical impact of the genomic technology revolution will be the elucidation of mechanisms of cancer pathogenesis, leading to improvements in the diagnosis of cancer and the selection of cancer treatment. Next-generation sequencing technologies have accelerated the characterization of a tumor, leading to the comprehensive discovery of all the major alterations in a given cancer genome, followed by the translation of this information using computational and immunoinformatics approaches to cancer diagnostics and therapeutic efforts. In the current article, we review various components of cancer immunoinformatics applied to a series of fields of cancer research, including computational tools for cancer mutation detection, cancer mutation and immunological databases, and computational vaccinology.
Identifiants
pubmed: 36398967
pii: 6832429
doi: 10.1093/bfgp/elac041
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-8Informations de copyright
© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.