Differential involvement of germline pathogenic variants in breast cancer genes between DCIS and low-grade invasive cancers.
Genetics, Medical
Journal
Journal of medical genetics
ISSN: 1468-6244
Titre abrégé: J Med Genet
Pays: England
ID NLM: 2985087R
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
28
06
2022
accepted:
14
11
2022
medline:
24
7
2023
pubmed:
29
11
2022
entrez:
28
11
2022
Statut:
ppublish
Résumé
To investigate frequency of germline pathogenic variants (PVs) in women with ductal carcinoma in situ (DCIS) and grade 1 invasive breast cancer (G1BC). We undertook 30/311 (9.6%) with DCIS and 16/392 with G1BC (4.1%) had a DCIS is more likely to be associated with both
Identifiants
pubmed: 36442995
pii: jmg-2022-108790
doi: 10.1136/jmg-2022-108790
doi:
Substances chimiques
BRCA1 Protein
0
BRCA2 Protein
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
740-746Subventions
Organisme : Department of Health
ID : IS-BRC-1215-20007
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.