Abdominal Mass in a Phenotypic Female with 46,XY Differences in Sex Development.


Journal

Urology
ISSN: 1527-9995
Titre abrégé: Urology
Pays: United States
ID NLM: 0366151

Informations de publication

Date de publication:
03 2023
Historique:
received: 23 11 2022
accepted: 27 11 2022
pubmed: 23 12 2022
medline: 28 3 2023
entrez: 22 12 2022
Statut: ppublish

Résumé

We present a case of a large intra-abdominal mass found to be localized pure seminoma within a retained gonad of a 53-year-old phenotypic female with 46,XY differences in sex development (DSD) and androgen insensitivity syndrome (AIS). Our management included extirpation of the mass with contralateral gonadectomy. Historically, patients with AIS would undergo gonadectomy to mitigate the lifetime risk of testicular germ cell tumor development; however, growing evidence suggests safety in retention and surveillance of these gonads into adulthood. This case highlights the importance of lifetime surveillance of patients with 46,XY DSD who elect to retain their gonads.

Identifiants

pubmed: 36549576
pii: S0090-4295(22)01061-5
doi: 10.1016/j.urology.2022.11.039
pii:
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13-e16

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Ridwan Alam (R)

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.

Andrew T Gabrielson (AT)

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.

Matthew J Rabinowitz (MJ)

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.

Max Kates (M)

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.

Heather N Di Carlo (HN)

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: hdicarl1@jhmi.edu.

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Classifications MeSH