Change in health outcomes for First Nations children with chronic wet cough: rationale and study protocol for a multi-centre implementation science study.
Chronic wet cough
First Nations children
Knowledge Translation
Protracted bacterial bronchitis
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
29 Dec 2022
29 Dec 2022
Historique:
received:
07
04
2022
accepted:
02
11
2022
entrez:
29
12
2022
pubmed:
30
12
2022
medline:
3
1
2023
Statut:
epublish
Résumé
In children, chronic wet cough may be a sign of underlying lung disease, including protracted bacterial bronchitis (PBB) and bronchiectasis. Chronic (> 4 weeks in duration) wet cough (without indicators pointing to alternative causes) that responds to antibiotic treatment is diagnostic of PBB. Timely recognition and management of PBB can prevent disease progression to irreversible bronchiectasis with lifelong consequences. However, detection and management require timely health-seeking by carers and effective management by clinicians. We aim to improve (a) carer health-seeking for chronic wet cough in their child and (b) management of chronic wet cough in children by clinicians. We hypothesise that implementing a culturally integrated program, which is informed by barriers and facilitators identified by carers and health practitioners, will result in improved lung health of First Nations children, and in the future, a reduced the burden of bronchiectasis through the prevention of the progression of protracted bacterial bronchitis to bronchiectasis. This study is a multi-centre, pseudorandomised, stepped wedge design. The intervention is the implementation of a program. The program has two components: a knowledge dissemination component and an implementation component. The implementation is adapted to each study site using a combined Aboriginal Participatory Action Research and an Implementation Science approach, guided by the Consolidated Framework of Implementation Research. There are three categories of outcome measures related to (i) health (ii) cost, and (iii) implementation. We will measure health-seeking as the proportion of parents seeking help for their child in a 6-month period before the intervention and the same 6-month period (i.e., the same six calendar months) thereafter. The parent-proxy, Cough-specific Quality of Life (PC-QoL) will be the primary health-related outcome measure. We hypothesise that a tailored intervention at each site will result in improved health-seeking for carers of children with a chronic wet cough and improved clinician management of chronic wet cough. In addition, we expect this will result in improved lung health outcomes for children with a chronic wet cough. Australian New Zealand Clinical Trials Registry; ACTRN12622000430730 , registered 16 March 2022, Retrospectively registered.
Sections du résumé
BACKGROUND
BACKGROUND
In children, chronic wet cough may be a sign of underlying lung disease, including protracted bacterial bronchitis (PBB) and bronchiectasis. Chronic (> 4 weeks in duration) wet cough (without indicators pointing to alternative causes) that responds to antibiotic treatment is diagnostic of PBB. Timely recognition and management of PBB can prevent disease progression to irreversible bronchiectasis with lifelong consequences. However, detection and management require timely health-seeking by carers and effective management by clinicians. We aim to improve (a) carer health-seeking for chronic wet cough in their child and (b) management of chronic wet cough in children by clinicians. We hypothesise that implementing a culturally integrated program, which is informed by barriers and facilitators identified by carers and health practitioners, will result in improved lung health of First Nations children, and in the future, a reduced the burden of bronchiectasis through the prevention of the progression of protracted bacterial bronchitis to bronchiectasis.
METHODS
METHODS
This study is a multi-centre, pseudorandomised, stepped wedge design. The intervention is the implementation of a program. The program has two components: a knowledge dissemination component and an implementation component. The implementation is adapted to each study site using a combined Aboriginal Participatory Action Research and an Implementation Science approach, guided by the Consolidated Framework of Implementation Research. There are three categories of outcome measures related to (i) health (ii) cost, and (iii) implementation. We will measure health-seeking as the proportion of parents seeking help for their child in a 6-month period before the intervention and the same 6-month period (i.e., the same six calendar months) thereafter. The parent-proxy, Cough-specific Quality of Life (PC-QoL) will be the primary health-related outcome measure.
DISCUSSION
CONCLUSIONS
We hypothesise that a tailored intervention at each site will result in improved health-seeking for carers of children with a chronic wet cough and improved clinician management of chronic wet cough. In addition, we expect this will result in improved lung health outcomes for children with a chronic wet cough.
TRIAL REGISTRATION
BACKGROUND
Australian New Zealand Clinical Trials Registry; ACTRN12622000430730 , registered 16 March 2022, Retrospectively registered.
Identifiants
pubmed: 36581812
doi: 10.1186/s12890-022-02219-0
pii: 10.1186/s12890-022-02219-0
pmc: PMC9798941
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
492Subventions
Organisme : National Health and Medical Research Council
ID : APP1170735
Informations de copyright
© 2022. Crown.
Références
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Respirology. 2020 Apr;25(4):383-392
pubmed: 31344317
Eur Respir J. 2017 Aug 24;50(2):
pubmed: 28838975
ERJ Open Res. 2019 Dec 08;5(4):
pubmed: 31832431
Implement Sci. 2009 Aug 07;4:50
pubmed: 19664226
NPJ Prim Care Respir Med. 2017 Jun 26;27(1):42
pubmed: 28652602
Int J Equity Health. 2016 Mar 10;15:47
pubmed: 26965040
Glob Health Promot. 2015 Mar;22(1):21-31
pubmed: 24842989
Med J Aust. 2006 Apr 17;184(8):398-403
pubmed: 16618239
J Allergy Clin Immunol. 2013 Apr;131(4):1069-74
pubmed: 23146374
Ann Intern Med. 2013 Feb 5;158(3):200-7
pubmed: 23295957
Qual Health Res. 2016 Nov;26(13):1753-1760
pubmed: 26613970
Pediatr Pulmonol. 2008 Jun;43(6):519-31
pubmed: 18435475
Public Health Res Pract. 2021 Mar 10;31(1):
pubmed: 33690783
Aust Health Rev. 2011 Nov;35(4):512-9
pubmed: 22126958
BMJ. 2010 Mar 23;340:c869
pubmed: 20332511
Int J Qual Health Care. 2007 Dec;19(6):349-57
pubmed: 17872937
Trials. 2014 Apr 23;15:139
pubmed: 24755011
Thorax. 2008 Apr;63 Suppl 3:iii1-iii15
pubmed: 17905822
Health Res Policy Syst. 2021 Sep 22;19(1):127
pubmed: 34551774
Chest. 2012 Apr;141(4):1018-1024
pubmed: 21885727
Lancet. 2018 Sep 8;392(10150):866-879
pubmed: 30215382
J Biomed Inform. 2019 Jul;95:103208
pubmed: 31078660
Chest. 2017 Apr;151(4):884-890
pubmed: 28143696
Adm Policy Ment Health. 2011 Mar;38(2):65-76
pubmed: 20957426
Chest. 2021 Jan;159(1):249-258
pubmed: 32673622
BMC Res Notes. 2015 May 16;8:199
pubmed: 25981585
J Paediatr Child Health. 2019 Jul;55(7):833-843
pubmed: 30444010