Differential rates of germline heterozygote and mosaic variants in


Journal

Journal of medical genetics
ISSN: 1468-6244
Titre abrégé: J Med Genet
Pays: England
ID NLM: 2985087R

Informations de publication

Date de publication:
09 2023
Historique:
received: 25 09 2022
accepted: 22 12 2022
medline: 23 8 2023
pubmed: 5 1 2023
entrez: 4 1 2023
Statut: ppublish

Résumé

NF2-related schwannomatosis is an autosomal dominant tumour predisposition condition that causes multiple benign tumours of the nervous system, especially schwannomas. This results from germline pathogenic variants in the

Identifiants

pubmed: 36599646
pii: jmg-2022-108960
doi: 10.1136/jmg-2022-108960
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

838-841

Subventions

Organisme : Department of Health
ID : IS-BRC-1215-20007
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: DGE is an National Institute for Health Research senior investigator.

Auteurs

D Gareth Evans (DG)

Division of Evolution and Genomic Science, St Mary's Hospital, Manchester Academic Health Sciences Centre (MAHSC), University of Manchester, Manchester, UK gareth.evans@mft.nhs.uk.

George J Burghel (GJ)

Genomic Diagnostic Laboratory, Manchester University NHS Foundation Trust, Manchester, UK.

Miriam Jane Smith (MJ)

Genetic Medicine, University of Manchester, Manchester, UK.

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Classifications MeSH