Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
13
06
2022
accepted:
11
11
2022
pubmed:
5
1
2023
medline:
21
1
2023
entrez:
4
1
2023
Statut:
ppublish
Résumé
Bacterial abortive-infection systems limit the spread of foreign invaders by shutting down or killing infected cells before the invaders can replicate
Identifiants
pubmed: 36599979
doi: 10.1038/s41586-022-05559-3
pii: 10.1038/s41586-022-05559-3
doi:
Substances chimiques
CRISPR-Associated Proteins
0
DNA
9007-49-2
DNA, Single-Stranded
0
RNA
63231-63-0
Cas12a protein
EC 3.1.-
RNA, Guide, CRISPR-Cas Systems
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
588-594Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM138080
Pays : United States
Informations de copyright
© 2023. The Author(s).
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