An international survey of current management practices for polymyalgia rheumatica by general practitioners and rheumatologists.


Journal

Rheumatology (Oxford, England)
ISSN: 1462-0332
Titre abrégé: Rheumatology (Oxford)
Pays: England
ID NLM: 100883501

Informations de publication

Date de publication:
01 08 2023
Historique:
accepted: 13 12 2022
received: 21 10 2022
medline: 3 8 2023
pubmed: 14 1 2023
entrez: 13 1 2023
Statut: ppublish

Résumé

To explore current management practices for PMR by general practitioners (GPs) and rheumatologists including implications for clinical trial recruitment. An English language questionnaire was constructed by a working group of rheumatologists and GPs from six countries. The questionnaire focused on: 1: Respondent characteristics; 2: Referral practices; 3: Treatment with glucocorticoids; 4: Diagnostics; 5: Comorbidities; and 6: Barriers to research. The questionnaire was distributed to rheumatologists and GPs worldwide via members of the International PMR/Giant Cell Arteritis Study Group. In total, 394 GPs and 937 rheumatologists responded to the survey. GPs referred a median of 25% of their suspected PMR patients for diagnosis and 50% of these were returned to their GP for management. In general, 39% of rheumatologists evaluated patients with suspected PMR >2 weeks after referral, and a median of 50% of patients had started prednisolone before rheumatologist evaluation. Direct comparison of initial treatment showed that the percentage prescribing >25 mg prednisolone daily for patients was 30% for GPs and 12% for rheumatologists. Diagnostic imaging was rarely used. More than half (56%) of rheumatologists experienced difficulties recruiting people with PMR to clinical trials. This large international survey indicates that a large proportion of people with PMR are not referred for diagnosis, and that the proportion of treatment-naive patients declined with increasing time from referral to assessment. Strategies are needed to change referral and management of people with PMR, to improve clinical practice and facilitate recruitment to clinical trials.

Identifiants

pubmed: 36637182
pii: 6986973
doi: 10.1093/rheumatology/keac713
doi:

Substances chimiques

Glucocorticoids 0
Prednisolone 9PHQ9Y1OLM

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2797-2805

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Auteurs

Agnete Overgaard Donskov (AO)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.

Sarah Louise Mackie (SL)

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Ellen Margrethe Hauge (EM)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Carlos Enrique Toro-Gutiérrez (CE)

Reference center for Osteoporosis, Rheumatology & Dermatology, Cali, Colombia.

Ib Tønder Hansen (IT)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Andrea Katharina Hemmig (AK)

Department of Rheumatology, University Hospital Basel, Basel, Switzerland.

Aatke Van der Maas (A)

Rheumatology Department, St Maartenskliniek, Nijmegen, Netherlands.

Tamer Gheita (T)

Rheumatology and Clinical Immunology, Cairo University, Cairo, Egypt.

Berit Dalsgaard Nielsen (BD)

Department of Medicine, The Regional Hospital in Horsens, Horsens, Denmark.

Karen M J Douglas (KMJ)

Department of Rheumatology, Dudley Group NHS FT, Dudley, UK.

Richard Conway (R)

Department of Rheumatology, St. James's Hospital, Dublin, Ireland.

Elena Rezus (E)

Department of Rheumatology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iasi, Romania.

Bhaskar Dasgupta (B)

Department of Rheumatology, Southend University Hospital, Southend, UK.

Sara Monti (S)

Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy.

Eric L Matteson (EL)

Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, USA.

Sebastian E Sattui (SE)

Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Mark Matza (M)

Rheumatology Unit, Massachusetts General Hospital, Boston, USA.

Vanessa Ocampo (V)

Rheumatology Department-Scarborough Health Network and Kensington Eye Institute, University of Toronto-Center for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, Toronto, Canada.

Margarita Gromova (M)

Faculty Therapy, Pirogov National Russian Research Medical University, Moscow, Russian Federation.

Rebecca Grainger (R)

Department of Medicine, University of Otago Wellington, Wellington, New Zealand.

Andrea Bran (A)

Department of Medicine, Universidad Francisco Marroquín, Guatemala City, Guatemala.

Simone Appenzeller (S)

Department of Orthopedics, Rheumatology and Traumatology-School of Medical Science, University of Campinas, Campinas, Brazil.

Annelise Goecke (A)

Rheumatology Section, Department of Medicine, University of Chile's Clinical Hospital, Santiago, Chile.

Nelly Colman (N)

Universidad Nacional de Asunción, Hospital de Clinicas, Asunción, Paraguay.

Helen I Keen (HI)

Medical School, UWA, Perth Australia, Rheumatology Department, Fiona Stanley Hospital, Perth, Australia.

Masataka Kuwana (M)

Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan.

Latika Gupta (L)

Department of Rheumatology, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, UK.
Department of Rheumatology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.

Babur Salim (B)

Rheumatology, Fauji Foundation Hospital Rawalpindi, Rawalpindi, Pakistan.

Ghita Harifi (G)

Rheumatology, Mediclinic Parkview Hospital, Dubai Health Authority, Dubai, United Arab Emirates.

Mariam Erraoui (M)

Faculty of Medicine and Pharmacy, Department of Rheumatology, Ibn Zohr University, Agadir, Morocco.

Nelly Ziade (N)

Rheumatology, Saint-Joseph University, Beirut, Lebanon.

Nizar Abdulateef Al-Ani (NA)

Rheumatology Unit, Department of Medicine, University of Baghdad, Bagdhad, Iraq.

Adeola Ajibade (A)

Department of Rheumatology, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, UK.
Rheumatology Unit, Internal Medicine Department, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

Johannes Knitza (J)

German Centrum for Immune Therapy, Friedrich-Alexander-University Erlangen Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.

Line Frølund (L)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.

Max Yates (M)

Centre for Epidemiology, Norwich Medical School, University of East Anglia, Norwich, UK.
Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich, UK.

Victor R Pimentel-Quiroz (VR)

Department of Rheumatology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru.
Universidad Científica del Sur, Lima, Perú.

Andre Marun Lyrio (AM)

Department of General Medicine/Rheumatology, Pontifical Catholic University of Campinas, Campinas, Brazil.

Maria Sandovici (M)

Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Kornelis S M Van der Geest (KSM)

Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Toby Helliwell (T)

School of Medicine, University of Staffordshire, Stafford, UK.

Elisabeth Brouwer (E)

Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Christian Dejaco (C)

Rheumatology, Medical University of Graz, Graz, Austria.
Rheumatology, Hospital of Bruneck (SABES-ASAA), Bruneck, Italy.

Kresten Krarup Keller (KK)

Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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