Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
17 01 2023
Historique:
received: 28 03 2022
accepted: 21 11 2022
entrez: 17 1 2023
pubmed: 18 1 2023
medline: 20 1 2023
Statut: epublish

Résumé

Dynamic processes on networks, be it information transfer in the Internet, contagious spreading in a social network, or neural signaling, take place along shortest or nearly shortest paths. Computing shortest paths is a straightforward task when the network of interest is fully known, and there are a plethora of computational algorithms for this purpose. Unfortunately, our maps of most large networks are substantially incomplete due to either the highly dynamic nature of networks, or high cost of network measurements, or both, rendering traditional path finding methods inefficient. We find that shortest paths in large real networks, such as the network of protein-protein interactions and the Internet at the autonomous system level, are not random but are organized according to latent-geometric rules. If nodes of these networks are mapped to points in latent hyperbolic spaces, shortest paths in them align along geodesic curves connecting endpoint nodes. We find that this alignment is sufficiently strong to allow for the identification of shortest path nodes even in the case of substantially incomplete networks, where numbers of missing links exceed those of observable links. We demonstrate the utility of latent-geometric path finding in problems of cellular pathway reconstruction and communication security.

Identifiants

pubmed: 36650144
doi: 10.1038/s41467-022-35181-w
pii: 10.1038/s41467-022-35181-w
pmc: PMC9845360
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

186

Subventions

Organisme : NLM NIH HHS
ID : R01 LM014017
Pays : United States

Informations de copyright

© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

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Auteurs

Maksim Kitsak (M)

Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, 2600 GA, Delft, The Netherlands. maksim.kitsak@gmail.com.
Network Science Institute, Northeastern University, 177 Huntington avenue, Boston, MA, 022115, USA. maksim.kitsak@gmail.com.

Alexander Ganin (A)

University of Virginia, Department of Systems and Information Engineering, Charlottesville, VA, 22904, USA.
U.S. Army Engineer Research and Development Center, Contractor, Concord, MA, 01742, USA.

Ahmed Elmokashfi (A)

Simula Metropolitan Center for Digital Engineering, Oslo, Norway.

Hongzhu Cui (H)

Bioinformatics and Computational Biology Program, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
Institute for Genomic Medicine, Columbia University Medical Center, New York, New York, USA.

Daniel A Eisenberg (DA)

Department of Operations Research, Naval Postgraduate School, Monterey, CA, 93943, USA.

David L Alderson (DL)

Department of Operations Research, Naval Postgraduate School, Monterey, CA, 93943, USA.

Dmitry Korkin (D)

Bioinformatics and Computational Biology Program, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
Computer Science Department, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
Data Science Program, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.

Igor Linkov (I)

U.S. Army Engineer Research and Development Center, Environmental Laboratory, Concord, MA, 01742, USA. igor.linkov@usace.mil.

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Classifications MeSH