Discordance between joint pain and imagery severity in the ankle joint and contributors of lower limb activity limitations in adults with haemophilia: A cross-sectional study.
activities of daily living
behaviour and behaviour mechanisms
diagnostic imaging
haemophilia
joint diseases
pain
Journal
Haemophilia : the official journal of the World Federation of Hemophilia
ISSN: 1365-2516
Titre abrégé: Haemophilia
Pays: England
ID NLM: 9442916
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
revised:
19
12
2022
received:
28
10
2022
accepted:
06
01
2023
pubmed:
26
1
2023
medline:
21
3
2023
entrez:
25
1
2023
Statut:
ppublish
Résumé
People with haemophilia (PwH) suffer from knee and ankle joint pain, but the association with structural damage remains underexplored. They report activity limitations but it is unclear which factors contribute to lower limb activity limitations (LL-AL). This study aimed (i) to analyse the association between ankle joint pain and structure and (ii) explore the contribution of haemophilia-related, individual and psychological factors to LL-AL in PwH. This study included 104 moderate/severe PwH. Ankle pain intensity was assessed with a numeric rating scale and pain sensitivity with algometry (pressure pain threshold (PPT Only low correlations were found between ankle pain intensity and structure (IPSG-MRI, HEAD-US). PPT No meaningful associations were found between ankle pain and structural damage, suggesting that other factors may contribute to PwH's ankle pain. In contrast, mainly haemophilia-related factors explained LL-AL variance.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
648-657Subventions
Organisme : European Association for Haemophilia and Allied Disorders: Research Grant 2019
Organisme : Swedish Orphan Biovitrum (SOBI)
Organisme : Universiteit Antwerpen
ID : 40017
Informations de copyright
© 2023 John Wiley & Sons Ltd.
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