Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males.
exercise
high altitude
skeletal muscle blood flow
sympathetic nervous system
α-adrenergic receptors
Journal
American journal of physiology. Regulatory, integrative and comparative physiology
ISSN: 1522-1490
Titre abrégé: Am J Physiol Regul Integr Comp Physiol
Pays: United States
ID NLM: 100901230
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
pmc-release:
01
04
2024
pubmed:
31
1
2023
medline:
21
3
2023
entrez:
30
1
2023
Statut:
ppublish
Résumé
Sympathetic transduction is reduced following chronic high-altitude (HA) exposure; however, vascular α-adrenergic signaling, the primary mechanism mediating sympathetic vasoconstriction at sea level (SL), has not been examined at HA. In nine male lowlanders, we measured forearm blood flow (Doppler ultrasound) and calculated changes in vascular conductance (ΔFVC) during
Identifiants
pubmed: 36717165
doi: 10.1152/ajpregu.00230.2022
pmc: PMC10026988
doi:
Substances chimiques
Adrenergic Agents
0
Vasoconstrictor Agents
0
Phenylephrine
1WS297W6MV
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
R457-R469Subventions
Organisme : HHS | National Institutes of Health (NIH)
ID : NIH 1F32HL137285-0
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