A Comparison of Hypothesis-Driven and Data-Driven Research: A Case Study in Multimodal Data Science in Gut-Brain Axis Research.


Journal

Computers, informatics, nursing : CIN
ISSN: 1538-9774
Titre abrégé: Comput Inform Nurs
Pays: United States
ID NLM: 101141667

Informations de publication

Date de publication:
01 Jul 2023
Historique:
pmc-release: 01 07 2024
medline: 10 7 2023
pubmed: 3 2 2023
entrez: 2 2 2023
Statut: epublish

Résumé

Data science, bioinformatics, and machine learning are the advent and progression of the fourth paradigm of exploratory science. The need for human-supported algorithms to capture patterns in big data is at the center of personalized healthcare and directly related to translational research. This paper argues that hypothesis-driven and data-driven research work together to inform the research process. At the core of these approaches are theoretical underpinnings that drive progress in the field. Here, we present several exemplars of research on the gut-brain axis that outline the innate values and challenges of these approaches. As nurses are trained to integrate multiple body systems to inform holistic human health promotion and disease prevention, nurses and nurse scientists serve an important role as mediators between this advancing technology and the patients. At the center of person-knowing, nurses need to be aware of the data revolution and use their unique skills to supplement the data science cycle from data to knowledge to insight.

Identifiants

pubmed: 36730994
doi: 10.1097/CIN.0000000000000954
pii: 00024665-990000000-00058
pmc: PMC10102251
mid: NIHMS1814644
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

497-506

Subventions

Organisme : Intramural NIH HHS
ID : Z99 CL999999
Pays : United States

Informations de copyright

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Caitlin Dreisbach (C)

Author Affiliations: Data Science Institute, Columbia University, New York, NY (Dr Dreisbach); and Translational Biobehavioral and Health Disparities Branch, National Institutes of Health Clinical Center (Dr Maki), Bethesda, MD.

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