Small Molecule-Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids.
DNA
DNA nanotechnology
antisense oligonucleotides
cyanuric acid
gene silencing
hydrogels
stimuli responsive
supramolecular
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
revised:
18
11
2022
received:
01
10
2022
medline:
27
4
2023
pubmed:
9
2
2023
entrez:
8
2
2023
Statut:
ppublish
Résumé
Deoxyribonucleic acid (DNA) hydrogels are a unique class of programmable, biocompatible materials able to respond to complex stimuli, making them valuable in drug delivery, analyte detection, cell growth, and shape-memory materials. However, unmodified DNA hydrogels in the literature are very soft, rarely reaching a storage modulus of 10
Identifiants
pubmed: 36752390
doi: 10.1002/advs.202205713
pmc: PMC10131789
doi:
Substances chimiques
Nucleic Acids
0
Hydrogels
0
DNA
9007-49-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2205713Subventions
Organisme : Canada Council for the Arts
Organisme : NSERC Discovery
ID : RGPIN-2018-05243
Organisme : Canada Research Chair Tier 2 Award
ID : 950-231953
Organisme : Canada Research Chairs
ID : 950-231953
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : 2018-05243
Organisme : NSERC Vanier Scholarship
Organisme : Fonds de Recherche du Québec - Nature et Technologie
Informations de copyright
© 2023 The Authors. Advanced Science published by Wiley-VCH GmbH.
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