Immunosuppressive Bibenzyl-phenylpropane Hybrids from Dendrobium devonianum.


Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 13 12 2022
accepted: 16 02 2023
pubmed: 17 2 2023
medline: 25 3 2023
entrez: 16 2 2023
Statut: ppublish

Résumé

Two new bibenzyl-phenylpropane hybrids, dendrophenols A and B (1 and 2), along with nine known bibenzyls, were isolated from the aerial part of Dendrobium devonianum Paxt. Their structures were determined by extensive spectroscopic methods and methylation. Bioassays revealed that compounds 1-9 were specifically immunosuppressive to T lymphocytes with IC

Identifiants

pubmed: 36795028
doi: 10.1002/cbdv.202201185
doi:

Substances chimiques

Bibenzyls 0
Free Radical Scavengers 0
cumene 8Q54S3XE7K

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202201185

Subventions

Organisme : National Natural Science Foundation of China
ID : 31860097
Organisme : Yunnan Province

Informations de copyright

© 2023 Wiley-VHCA AG, Zurich, Switzerland.

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Auteurs

Rui Zhan (R)

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650050, P. R. China.

Xin-Yue Zhang (XY)

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650050, P. R. China.

Zhi-Yuan Li (ZY)

Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.

Bo Liu (B)

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650050, P. R. China.

Ye-Gao Chen (YG)

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650050, P. R. China.

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