Smartphone-based 3D-printed electrochemiluminescence enzyme biosensor for reagentless glucose quantification in real matrices.

Glucose / analysis Luminol Glucose Oxidase / metabolism Smartphone Hydrogen Peroxide Luminescent Measurements Biosensing Techniques / methods Electrodes Printing, Three-Dimensional Electrochemical Techniques
3D printing Biosensor Conductive PLA Electrochemiluminescence Glucose Luminol

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
01 May 2023
Historique:
received: 20 11 2022
revised: 21 01 2023
accepted: 08 02 2023
pubmed: 24 2 2023
medline: 15 3 2023
entrez: 23 2 2023
Statut: ppublish

Résumé

Three-dimensional (3D) printed electrochemical devices are increasingly used in point-of-need and point-of-care testing. They show several advantages such as simple fabrication, low cost, fast response, and excellent selectivity and sensitivity in small sample volumes. However, there are only a few examples of analytical devices combining 3D-printed electrodes with electrochemiluminescence (ECL) detection, an electrochemical detection principle widely employed in clinical chemistry analysis. Herein, a portable, 3D-printed miniaturized ECL biosensor for glucose detection has been developed, based on the luminol/H

Identifiants

DOI: 10.1016/j.bios.2023.115146 PMID: 36821991
pubmed: 36821991
pii: S0956-5663(23)00088-X
doi: 10.1016/j.bios.2023.115146
pii:
doi:

Substances chimiques

Glucose IY9XDZ35W2
Luminol 5EXP385Q4F
Glucose Oxidase EC 1.1.3.4
Hydrogen Peroxide BBX060AN9V

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115146

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Massimo Guardigli and Francesco Paolucci report financial support was provided by MUR.

Auteurs

Donato Calabria (D)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy; Interdepartmental Centre for Industrial Aerospace Research (CIRI AEROSPACE), Alma Mater Studiorum-University of Bologna, Via Baldassarre Canaccini 12, I-47121, Forlì, Italy.

Elisa Lazzarini (E)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.

Andrea Pace (A)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.

Ilaria Trozzi (I)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.

Martina Zangheri (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy; Interdepartmental Centre for Industrial Agrofood Research (CIRI AGRO), Alma Mater Studiorum - University of Bologna, Via Quinto Bucci 336, I-47521, Cesena, Italy; Interdepartmental Centre for Industrial Research in Advanced Mechanical Engineering Applications and Materials Technology (CIRI MAM), Alma Mater Studiorum-University of Bologna, Viale Risorgimento 2, I-40136, Bologna, Italy.

Stefano Cinti (S)

Department of Pharmacy, University Naples Federico II, Via Domenico Montesano 49, I-80131, Naples, Italy; BAT Center-Interuniversity Center for Studies on Bioinspired Agro-Environmental Technology, University of Napoli "Federico II", 80055, Portici, Naples, Italy.

Marinella Difonzo (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.

Giovanni Valenti (G)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.

Massimo Guardigli (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy; Interdepartmental Centre for Industrial Aerospace Research (CIRI AEROSPACE), Alma Mater Studiorum-University of Bologna, Via Baldassarre Canaccini 12, I-47121, Forlì, Italy; Interdepartmental Centre for Industrial Research in Renewable Resources, Environment, Sea and Energy (CIRI FRAME), Alma Mater Studiorum - University of Bologna, Via Sant'Alberto 163, I-48123, Ravenna, Italy.

Francesco Paolucci (F)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy. Electronic address: francesco.paolucci@unibo.it.

Mara Mirasoli (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, I-40126, Bologna, Italy; Interdepartmental Centre for Industrial Aerospace Research (CIRI AEROSPACE), Alma Mater Studiorum-University of Bologna, Via Baldassarre Canaccini 12, I-47121, Forlì, Italy; Interdepartmental Centre for Industrial Research in Renewable Resources, Environment, Sea and Energy (CIRI FRAME), Alma Mater Studiorum - University of Bologna, Via Sant'Alberto 163, I-48123, Ravenna, Italy. Electronic address: mara.mirasoli@unibo.it.

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Classifications MeSH

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