Efficacy of a new nutraceutical formulation: L-tryptophan, probiotics, charcoal, chamomile, mint, and licorice (COLONIR®) in the improvement of gastrointestinal symptoms in subjects with irritable bowel syndrome.
Journal
Minerva gastroenterology
ISSN: 2724-5365
Titre abrégé: Minerva Gastroenterol (Torino)
Pays: Italy
ID NLM: 101777280
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
entrez:
1
3
2023
pubmed:
2
3
2023
medline:
3
3
2023
Statut:
ppublish
Résumé
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. IBS is characterized by recurrent chronic abdominal pain and altered bowel habits in the absence of organic damage. Although there are reviews and guidelines for treating IBS, the complexity and diversity of IBS presentation make treatment difficult. Treatment of IBS focuses on relieving symptoms as mild signs and symptoms can often be controlled by managing stress and by making changes in diet and lifestyle. The use of nutraceutical compounds has been advocated as a possible alternative treatment in patients with IBS. COLONIR An initial cohort of 1004 consecutive patients referred to 25 different Units of Internal Medicine a/o Gastroenterology in Italy to perform colonoscopy for intestinal symptoms was asked to participate. Patients were treated for 2 months with three doses of nutraceuticals/day after meals namely COLONIR After 2 months, 899 patients completed the follow-up. COLONIR These promising results, here reported, need to be confirmed, valuating the efficacy of COLONIR
Sections du résumé
BACKGROUND
BACKGROUND
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. IBS is characterized by recurrent chronic abdominal pain and altered bowel habits in the absence of organic damage. Although there are reviews and guidelines for treating IBS, the complexity and diversity of IBS presentation make treatment difficult. Treatment of IBS focuses on relieving symptoms as mild signs and symptoms can often be controlled by managing stress and by making changes in diet and lifestyle. The use of nutraceutical compounds has been advocated as a possible alternative treatment in patients with IBS. COLONIR
METHODS
METHODS
An initial cohort of 1004 consecutive patients referred to 25 different Units of Internal Medicine a/o Gastroenterology in Italy to perform colonoscopy for intestinal symptoms was asked to participate. Patients were treated for 2 months with three doses of nutraceuticals/day after meals namely COLONIR
RESULTS
RESULTS
After 2 months, 899 patients completed the follow-up. COLONIR
CONCLUSIONS
CONCLUSIONS
These promising results, here reported, need to be confirmed, valuating the efficacy of COLONIR
Identifiants
pubmed: 36856276
pii: S2724-5985.22.03282-X
doi: 10.23736/S2724-5985.22.03282-X
doi:
Substances chimiques
Charcoal
16291-96-6
Tryptophan
8DUH1N11BX
Flower Essences
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM