Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine.

Prilocaine Calorimetry, Differential Scanning Transition Temperature Chemical Phenomena Water
Anti-plasticizing effect of water Co-amorphous Glass transition Molecular mobility Prilocaine-nicotinamide

Journal

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
ISSN: 1873-3441
Titre abrégé: Eur J Pharm Biopharm
Pays: Netherlands
ID NLM: 9109778

Informations de publication

Date de publication:
May 2023
Historique:
received: 30 11 2022
revised: 10 02 2023
accepted: 27 02 2023
medline: 25 4 2023
pubmed: 7 3 2023
entrez: 6 3 2023
Statut: ppublish

Résumé

It is generally recognized that water, acting as a plasticizer, increases molecular mobility, leading to a decrease of the glass transition temperature (T

Identifiants

DOI: 10.1016/j.ejpb.2023.02.015 PMID: 36878408
pubmed: 36878408
pii: S0939-6411(23)00057-7
doi: 10.1016/j.ejpb.2023.02.015
pii:
doi:

Substances chimiques

Prilocaine 046O35D44R
Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-6

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Xiaoyue Xu (X)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.

Thomas Rades (T)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.

Holger Grohganz (H)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. Electronic address: holger.grohganz@sund.ku.dk.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Anilides › Prilocaïne › Thermal investigation on hydrated co-amorphous...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse thermique différentielle › Calorimétrie différentielle à balayage › Thermal investigation on hydrated co-amorphous...
questionsmedicales.fr › Phénomènes physiques › Thermodynamique › Température de transition › Thermal investigation on hydrated co-amorphous...
questionsmedicales.fr › Phénomènes chimiques › Thermal investigation on hydrated co-amorphous...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Thermal investigation on hydrated co-amorphous...