In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors.
CD34
Conventional dendritic cells
Cord blood
Dendritic cells
Hematopoietic stem cells
In vitro differentiation
Mesenchymal stromal cells
Plasmacytoid dendritic cell
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2023
2023
Historique:
entrez:
11
3
2023
pubmed:
12
3
2023
medline:
15
3
2023
Statut:
ppublish
Résumé
Dendritic cells (DCs) are professional antigen-presenting cells controlling the activation of T cells and thus regulating adaptive immune response against pathogens or tumors. Modeling human DC differentiation and function is crucial for our understanding of immune response and the development of new therapies. Considering DC rarity in human blood, in vitro systems allowing their faithful generation are needed. This chapter will describe a DC differentiation method based on the co-culture of CD34
Identifiants
pubmed: 36905513
doi: 10.1007/978-1-0716-2938-3_9
doi:
Substances chimiques
Antigens, CD34
0
Cell Adhesion Molecules
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
121-132Informations de copyright
© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
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