Development of an Automated Capillary Immunoassay to Detect Prion Glycotypes in Creutzfeldt-Jakob Disease.

Humans Creutzfeldt-Jakob Syndrome / diagnosis Prions / metabolism Brain / metabolism Prion Proteins / genetics Peptide Hydrolases / metabolism Codon / metabolism
Creutzfeldt-Jakob disease Prion capillary electrophoresis

Journal

Laboratory investigation; a journal of technical methods and pathology
ISSN: 1530-0307
Titre abrégé: Lab Invest
Pays: United States
ID NLM: 0376617

Informations de publication

Date de publication:
03 2023
Historique:
received: 10 10 2021
revised: 23 09 2022
accepted: 07 11 2022
entrez: 16 3 2023
pubmed: 17 3 2023
medline: 21 3 2023
Statut: ppublish

Résumé

Creutzfeldt-Jakob disease (CJD) comprises a group of transmissible neurodegenerative diseases with vast phenotypic diversity. Sporadic CJD heterogeneity is predominantly influenced by the genotype at codon 129 of the prion-encoding gene and the molecular weight of PrP

Identifiants

DOI: 10.1016/j.labinv.2022.100029 PMID: 36925197
pubmed: 36925197
pii: S0023-6837(22)00620-1
doi: 10.1016/j.labinv.2022.100029
pii:
doi:

Substances chimiques

Prions 0
Prion Proteins 0
Peptide Hydrolases EC 3.4.-
Codon 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

100029

Informations de copyright

Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.

Auteurs

Jennifer Myskiw (J)

One Health Division, Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Manitoba, Canada; Department of Medical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Lise Lamoureux (L)

One Health Division, Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Manitoba, Canada.

Anne Peterson (A)

One Health Division, Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Manitoba, Canada.

David Knox (D)

One Health Division, Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Manitoba, Canada.

Gerard H Jansen (GH)

Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Michael B Coulthart (MB)

Canadian Creutzfeldt-Jakob Disease Surveillance System, Public Health Agency of Canada, Ottawa, Ontario, Canada.

Stephanie A Booth (SA)

One Health Division, Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Manitoba, Canada; Department of Medical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: stephanie.booth@phac-aspc.gc.ca.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Development of an Automated Capillary...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie de Creutzfeldt-Jakob › Development of an Automated Capillary...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Prions › Development of an Automated Capillary...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Development of an Automated Capillary...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Prions › Protéines prion › Development of an Automated Capillary...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Development of an Automated Capillary...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Codon › Development of an Automated Capillary...