Megakaryocytes respond during sepsis and display innate immune cell behaviors.
infectious
innate
megakaryocyte
platelet
sepsis
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
10
2022
accepted:
07
02
2023
entrez:
20
3
2023
pubmed:
21
3
2023
medline:
22
3
2023
Statut:
epublish
Résumé
Megakaryocytes (MKs) are precursors to platelets, the second most abundant cells in the peripheral circulation. However, while platelets are known to participate in immune responses and play significant functions during infections, the role of MKs within the immune system remains largely unexplored. Histological studies of sepsis patients identified increased nucleated CD61
Identifiants
pubmed: 36936945
doi: 10.3389/fimmu.2023.1083339
pmc: PMC10019826
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1083339Informations de copyright
Copyright © 2023 Frydman, Ellett, Jorgensen, Marand, Zukerberg, Selig, Tessier, Wong, Olaleye, Vanderburg, Fox, Tompkins and Irimia.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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