Morphometric Assessment of the Ciliary Body in Patients With Marfan Syndrome and Ectopia Lentis: A Quantitative Study Using Ultrasound Biomicroscopy.


Journal

American journal of ophthalmology
ISSN: 1879-1891
Titre abrégé: Am J Ophthalmol
Pays: United States
ID NLM: 0370500

Informations de publication

Date de publication:
07 2023
Historique:
received: 08 11 2022
revised: 28 02 2023
accepted: 05 03 2023
medline: 6 6 2023
pubmed: 23 3 2023
entrez: 22 3 2023
Statut: ppublish

Résumé

To explore the biometric characteristics of the ciliary body in patients with Marfan syndrome (MFS) and ectopia lentis (EL). Cross-sectional study. Seventy-two consecutive patients with MFS and EL and 72 nondiseased control subjects were recruited. Ciliary body biometric parameters such as ciliary muscle cross-sectional area at 2000 µm from the scleral spur (CMA2000), ciliary muscle thickness at 1000 µm from the scleral spur (CMT1000), and maximum ciliary body thickness (CBTmax) were measured from multiple directions with ultrasound biomicroscopy (UBM). The relationship between ciliary body parameters and other ocular characteristics was also evaluated. Average CMA2000, CMT1000, and CBTmax were 0.692 ± 0.015 mm Patients with MFS and EL had thinner ciliary muscles, shorter ciliary processes, and a higher prevalence of ciliary body thinning, especially those with MSP. Both the extent and direction of subluxation were associated with ciliary body biometry.</ABSTRACT>.

Identifiants

pubmed: 36948371
pii: S0002-9394(23)00101-0
doi: 10.1016/j.ajo.2023.03.003
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

24-31

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Wan-Nan Jia (WN)

From the Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences; and the Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China.

Qian-Yi Wang (QY)

From the Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences; and the Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China.

Ling-Ling Niu (LL)

From the Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences; and the Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China.

Ze-Xu Chen (ZX)

From the Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences; and the Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China. Electronic address: chenzexu430@163.com.

Yong-Xiang Jiang (YX)

From the Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences; and the Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China. Electronic address: yongxiang_jiang@163.com.

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Classifications MeSH